Results 41 to 50 of about 143,826 (243)

Untargeted Lipidomic Analysis to Broadly Characterize the Effects of Pathogenic and Non-Pathogenic Staphylococci on Mammalian Lipids [PDF]

, 2018
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the ...
Baker, Paul RS, Contaifer, Daniel, Jr., Ekroos, Kim, Jefferson, Kimberly K., Kumar, Naren Gajenthra, Wijesinghe, Dayanjan S.   +5 more
core   +4 more sources

Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Fat mass is controlled by the balance of triacylglycerol (TAG) degradation and synthesis. Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are key players in TAG catabolism providing fatty acids (FAs) as energy ...
K. Brejchova, F. Radner, L. Balas, V. Paluchová, T. Cajka, H. Chodounská, E. Kudová, Margarita Schratter, R. Schreiber, T. Durand, R. Zechner, O. Kuda   +11 more
semanticscholar   +1 more source

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]

, 2007
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C., Christoffolete, Marcelo A., D'Eon, Tara M., Greenberg, Andrew S., Imachi, Hitomi, Miyoshi, Hideaki, Obin, Martin S., Perfield, James W., II, Ribeiro, Miriam O., Rogers, Nicole H., Souza, Sandra C., Stancheva, Zlatina S., Strissel, Katherine J.   +12 more
core   +1 more source

A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity

Journal of Lipid Research, 2021
Lipases constitute an important class of water-soluble enzymes that catalyze the hydrolysis of hydrophobic triacylglycerol (TAG). Their enzymatic activity is typically measured using multistep procedures involving isolation and quantification of the ...
Sujith Rajan, Hazel C. de Guzman, Thomas Palaia, Ira J. Goldberg, M. Mahmood Hussain   +4 more
doaj  

Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks? [PDF]

, 2013
In this review, we explore the concept of ‘double diabetes’, a combination of type 1 diabetes with features of insulin resistance and type 2 diabetes.
A Caixas, AM Taylor, B Conway, B Teupe, B. M. Fisher, BF Voight, CT Prince, D Williams, D Yazici, DB Savage, DM Maahs, DM Maahs, DM Nathan, EA Nikkila, ER Christ, ES Kilpatrick, G Pambianco, G Perseghin, G Perseghin, G Roglic, G Ruotolo, H. M. Colhoun, HM Colhoun, IE Schauer, J Frystyk, J Guy, J Yip, J-L Selam, J. R. Petrie, JA Edge, JB Ferriss, JC Zgibor, JQ Purnell, JQ Purnell, JR Erbey, JR Petrie, JT Lahtela, KJ Nadeau, L Hodson, LM Thorn, M Kacerovsky, MR Taskinen, MR Taskinen, MR Taskinen, N Chaturvedi, N Sattar, N. Sattar, P Nevalainen, P Petruzzo, R Sinha, RA Heptulla, RW James, S Makimattila, S Norbert, S Vella, S. J. Cleland, SC Bain, SD Sibley, SJ Livingstone, SR Vethakkan, The Diabetes Control and Complications Trial Research Group, TJ Orchard, TJ Wilkin   +62 more
core   +3 more sources

The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci [PDF]

, 2017
The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which contributes to the modulation of
Alvarez, Hector Manuel, Gago, Gabriela Marisa, Gramajo, Hugo Cesar, Hernández, Martín Alejandro, Lara, María Julia   +4 more
core   +1 more source

Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]

, 2015
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K., Caslake, Muriel J., Cooney, Josephine, GHAFOURI, Khloud, Gill, Jason M.R., Wilson, John   +5 more
core   +1 more source

Characterization of the enzymatic activity and physiological function of the lipid droplet-associated triacylglycerol lipase AtOBL1.

New Phytologist, 2018
Similar to seeds, pollen tubes contain lipid droplets that store triacylglycerol (TAG), but the fate of this TAG as well as the enzymes involved in its breakdown are unknown.
Anna O Müller, T. Ischebeck
semanticscholar   +1 more source

Lipase activity in vesicular systems: Characterization of candida cylindracea lipase and its activity in polymerizable dialkylammonium surfactant vesicles [PDF]

, 1993
Lipase from Candida cylindracea (CCL) was incorporated into polymerizable positively charged dialkylammonium bromide surfactant vesicles. The enzyme was incorporated by the use of the dehydration-rehydration method or by incubation.
Engbersen, J.F.J., Franssen, M.C.R., Mosmuller, E.W.J.   +2 more
core   +4 more sources

Kinetics of the two-step hydrolysis of triacylglycerol by pancreatic lipases [PDF]

European Journal of Biochemistry, 1995
Pancreatic lipases catalyze the hydrolysis of triacylglycerol in a sequential manner. First, triacylglycerol is hydrolyzed to 1,2‐diacylglycerol, which is subsequently converted to 2‐monoacylglycerol. We studied the kinetics of trioleoylglycerol hydrolysis by rabbit and human pancreatic lipases. The products (acylglycerols and fatty acid) were analyzed
Pantelis Arzoglou, Vassilis Mougios, Athanasios Lykidis   +2 more
openaire   +3 more sources