Results 91 to 100 of about 3,371,113 (299)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Summons of freeholders to Frank's trial
This document is a legal writ issued by Samuel Dickinson and John Vining, two Justices of the Peace for Kent County. It outlines the commission assigned to James Wells, a constable, to summon several substantial freeholders, including Benjamin Chew ...
Kent County Court for the Trial of Negro Slaves
core +1 more source
Faire remonter les chiffres du Covid
Revue d'anthropologie des connaissancesThe Covid-19 pandemic had a profound effect on the production and circulation of health data. This article examines the conditions under which, in France, a form of “upstreaming” of data towards the central administration was organised at the peak of the
Marine Boisson, Jérôme Denis
doaj +1 more source
, 2012 Background: surgeons in the Netherlands, Canada and the US participate in the FAITH trial (Fixation using Alternative Implants for the Treatment of Hip fractures).
on behalf of the FAITH trial investigators +9 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Summons for testimony in the trial of Mingo and Jacob
This document is a summons issued under the authority of King George III, directing John Smithers, a constable of Kent County, to summon the sheriff, coroner, and freeholders Charles Hillyard, Charles Marim, William Rodney, John Banning, Vincent ...
Kent County Court for the Trial of Negro Slaves
core +1 more source
Transfer of Procedure in Criminal Matters in Romanian Legislation
EIRP Proceedings, 2009 Aware of the obligations assumed in fighting crime, Romania translated in itsinternal legislation the European Convention on the transfer of procedure in criminal matters,adopted in Strasbourg on 15 May 1972, ratified through Government’s Ordinance no.77/
Ion Rusu
doaj