Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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, 2015 Downy mildew has been identified as the primary pathogen plaguing our northeastern hop yards. This disease causes reduced yield, poor hop quality, and can cause the plant to die in severe cases.
Calderwood, Lily +7 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Organic Winter Wheat Variety Trial [PDF]
, 2016 In 2016, the University of Vermont Extension Northwest Crops and Soils Program evaluated 14 modern hard red winter wheat varieties to determine which varieties thrive in organic production systems.
Cummings, Erica +2 more
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Commentary on Spilsbury K, Petherick E, Cullum N, Nelson A, Nixon J & Mason S (2008) The role and potential contribution of clinical research nurses to clinical trials.Journal of Clinical Nursing17, 549–557 [PDF]
, 2008 Claire M. Rickard, Brigit Roberts
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Effects of Ten Different Exercise Interventions on Motor Function in Parkinson’s Disease Patients—A Network Me-a-Analysis of Randomized Controlled Trials [PDF]
, 2022 Zikang Hao, Xiaodan Zhang, Ping Chen
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Machine perfusion in clinical trials: the preservation solution bias [PDF]
, 2011 Nicolas Chatauret +4 more
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Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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