Results 11 to 20 of about 9,492,801 (363)
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
New England Journal of Medicine, 2020 Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection,
B. Cao +64 more
semanticscholar +1 more source
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
New England Journal of Medicine, 2020 Background World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19 ...
H. Pan +73 more
semanticscholar +1 more source
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.
New England Journal of Medicine, 2020 BACKGROUND There are limited data from randomized trials regarding whether volume-based, low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among male former and current smokers.
H. D. de Koning +23 more
semanticscholar +1 more source
Trial of Psilocybin versus Escitalopram for Depression.
New England Journal of Medicine, 2021 BACKGROUND Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking.
R. Carhart-Harris +9 more
semanticscholar +1 more source
A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis.
New England Journal of Medicine, 2020 BACKGROUND Nonalcoholic steatohepatitis (NASH) is a common disease that is associated with increased morbidity and mortality, but treatment options are limited.
P. Newsome +8 more
semanticscholar +1 more source
Prototype of running clinical trials in an untrustworthy environment using blockchain. [PDF]
, 2019 Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system.
Bhattacharya, Sanchita +2 more
core +3 more sources
For the benefit of others: reasons why women with breast cancer participate in RCTs [PDF]
, 2015 Introduction: Appreciation of the barriers and drivers affecting enrolment in randomised clinical trials (RCTs) is important for future trial design, communication and information provision.
Fallowfield, Lesley, Jenkins, Valerie
core +1 more source
Soundscape Optimization in Nursing Homes Through Raising Awareness in Nursing Staff With MoSART+
Frontiers in Psychology, 2022 IntroductionSoundscapes in nursing homes are often suboptimal for residents. This can cause them feeling anxious and unsafe, or develop behavioral and psychological problems.
Janouk Kosters +6 more
doaj +1 more source
Understanding controlled trials: Crossover trials
BMJ, 1998 This is the fifth of an occasional series on the methods of randomised controlled trials In a crossover trial subjects are randomly allocated to study arms where each arm consists of a sequence of two or more treatments given consecutively. The simplest model is the AB/BA study.
Sibbald, Bonnie, Roberts, Chris
openaire +4 more sources
Métropoles, 2019 Ageing in urban environments is a growing challenge for Western societies. Unfortunately, the issue remains under-addressed in the field of social sciences and little is known about it.
Loïc Riom +2 more
doaj +1 more source