Results 81 to 90 of about 9,492,801 (363)

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

A randomized-controlled trial of community-based transdiagnostic psychotherapy for veterans and internally displaced persons in Ukraine

Cambridge Prisms: Global Mental Health, 2021
Background There is limited research on community-based mental health interventions in former Soviet countries despite different contextual factors from where most research has been conducted.
Sergiy Bogdanov, Jura Augustinavicius, Judith K. Bass, Kristie Metz, Stephanie Skavenski, Namrita S. Singh, Quincy Moore, Emily E. Haroz, Jeremy Kane, Ben Doty, Laura Murray, Paul Bolton   +11 more
doaj   +1 more source

Contamination in complex healthcare trials:the falls in care homes (FinCH) study experience [PDF]

, 2020
BACKGROUND: Trials are at risk of contamination bias which can occur when participants in the control group are inadvertently exposed to the intervention.
Allen, F, Darby, J, Fox, C, Gordon, A L, Horne, J C, Leighton, P, Logan, P A, Robinson, K, Sims, Erika   +8 more
core   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Oat Variety Trial [PDF]

, 2016
Oats (Avena sativa L.) have a long history of production in the Northeast. Although most oats are planted for a cover crop or forage, grain oats are a potential revenue source for farmers.
Cubins, Julija, Cummings, Erica, Darby, Heather, Emick, Hillary   +3 more
core   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Text messaging and financial incentives to encourage weight loss in men with obesity: the Game of Stones feasibility RCT

Public Health Research, 2020
Background: In 2016, 26% of UK men were estimated to be obese. Systematic reviews suggest that few men engage in formal weight loss interventions that support weight reduction and improve health.
Stephan U Dombrowski, Matthew McDonald, Marjon van der Pol, Mark Grindle, Alison Avenell, Paula Carroll, Eileen Calveley, Andrew Elders, Nicola Glennie, Cindy M Gray, Fiona M Harris, Adrian Hapca, Claire Jones, Frank Kee, Michelle C McKinley, Rebecca Skinner, Martin Tod, Pat Hoddinott   +17 more
doaj   +1 more source

Estimation of clinical trial success rates and related parameters

Biostatistics, 2018
&NA; Previous estimates of drug development success rates rely on relatively small samples from databases curated by the pharmaceutical industry and are subject to potential selection biases.
Chi Heem Wong, K. W. Siah, A. Lo
semanticscholar   +1 more source

Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension

Nature Medicine, 2020
The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol reporting by providing evidence-based recommendations for the minimum set of items to be addressed.
S. Cruz Rivera, Xiaoxuan Liu, A. Chan, A. Denniston, M. Calvert, Ara Christopher Christopher David Hutan Jonathan J. La Darzi Holmes Yau Moher Ashrafian Deeks Ferrante di, A. Darzi, Christopher Holmes, Christopher Yau, D. Moher, H. Ashrafian, J. J. Deeks, Lavinia Ferrante di Ruffano, Livia Faes, P. Keane, Sebastian J. Vollmer, Aaron Y. Adrian Andre Andrew L. Maria Beatrice Cecilia S Lee Jonas Esteva Beam Panico Lee Haug Kelly Yau Mu, Aaron Y. Lee, Adrian Jonas, Andre Esteva, A. L. Beam, M. Panico, Cecilia S. Lee, Charlotte Haug, Christopher J. Kelly, C. Mulrow, Cyrus Espinoza, John Fletcher, Dina Paltoo, Elaine Manna, Gary Price, Gary S Collins, Hugh Harvey, James Matcham, João Monteiro, M. ElZarrad, Luke Oakden-Rayner, Melissa McCradden, Richard Savage, R. Golub, Rupa Sarkar, Samuel Rowley   +41 more
semanticscholar   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source