Results 91 to 100 of about 665,380 (279)

Trigonometric Function Solutions of Fractional Drinfeld's Sokolov -Wilson System

ITM Web of Conferences, 2017
In this paper, we construct exact trigonometric solutions of the space-time fractional classical Drinfeld's Sokolov-Wilson system by Modified Trial Equation Method (MTEM).
Koçak Zeynep Fidan, Yel Gülnur
doaj   +1 more source

The Cosmological Constant as an Eigenvalue of a Sturm-Liouville Problem and its Renormalization

, 2005
We discuss the case of massive gravitons and their relation with the cosmological constant, considered as an eigenvalue of a Sturm-Liouville problem. A variational approach with Gaussian trial wave functionals is used as a method to study such a problem.
Cherednikov I O, Cherednikov I O, Dubovsky S L, Fierz M, Garattini R, Remo Garattini, Rubakov V A, Sahni V, Straumann N, Visser M, Zakharov V I   +10 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Chiral Solitons with Bohm Potential by Modified Simple Equation Method and Trial Equation Scheme

Acta Physica Polonica A, 2018
In this paper we obtain soliton solutions to chiral nonlinear Schrodinger's equation with the Bohm potential by the modified simple equation method and trial equation method. Solitons and shock wave solutions are obtained. Additionally, singular periodic solutions are revealed as a by-product of these approaches and these are also listed. The existence
Belic, M., Moshokoa, S. P., Zhou, Qin, Yasar, E., Yildirim, Y., Biswas, A.   +5 more
openaire   +2 more sources

Efficient solutions of self-consistent mean field equations for dewetting and electrostatics in nonuniform liquids

, 2010
We use a new configuration-based version of linear response theory to efficiently solve self-consistent mean field equations relating an effective single particle potential to the induced density. The versatility and accuracy of the method is illustrated
John D. Weeks, L. P. Kadanoff, Zhonghan Hu   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Qualitative analysis and optical solitons for the (1+1)-dimensional Biswas-Milovic equation with parabolic law and nonlocal nonlinearity

Results in Physics
In this paper, the (1+1)-dimensional Biswas-Milovic equation with parabolic law and nonlocal nonlinearity is studied. Firstly, the Biswas-Milovic equation with parabolic law and nonlocal nonlinearity is transformed into ordinary differential equation ...
Zhao Li, Ejaz Hussain
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source