Results 71 to 80 of about 167,987 (303)

Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]

, 2015
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia, Gibbs EL, Iñaki Llodio, Johnson JM, José González-Alonso, Kameljit K. Kalsi, Niels H. Secher, Scott T. Chiesa, Steven J. Trangmar   +8 more
core   +2 more sources

Temporally Delayed Deployment of Photo‐Responsive Liquid Crystal Polymer Networks Toward Neural Interfaces

Advanced Healthcare Materials, EarlyView.
Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng, Eleanor Nguyen Jeakle, Mahjabeen Javed, Rajasree Gopala Krishnan, Thomas J. Smith, Yoo Jin Lee, Sahana Dhananjayan, Sasha M. George, Manivannan Sivaperuman Kalairaj, Ali Hasan Zuaiter, Majed O. Althumayri, Hatice Ceylan Koydemir, Joseph J. Pancrazio, Taylor H. Ware   +13 more
wiley   +1 more source

Variation in catheter management and predictors of trial without catheter success in men with AUR: results from the AUR-SNAPSHOT study

Continence
Background and objective: This study aimed to assess practice variation in the timing and management of trial without catheter (TWOC) following acute urinary retention (AUR) in Dutch hospitals. Secondary objectives were to identify clinical predictors of
Nadine Arina Maria van Merode, P.Y. Hermans, T. de Jong, B.M.A. Schout, C. Cobussen, J.P.A. van Basten, R. de Jongh, S. Mekke, H. Roshani, M.M. Nijenhuis, J.I.M. van Uhm, R.R. Kikkert, S. Tilli, J.F.A. Heesakkers, M. Duijn, E.P. van Haarst, A.M. Tijans, A. Noordzij, L. van Eerten-Koops, I. Bleumer, E.H. Tijhof, E.B. Cornel, L.P.W. Witte   +22 more
doaj   +1 more source

Outcomes of Early Endoscopic Realignment Versus Suprapubic Cystostomy and Delayed Urethroplasty for Pelvic Fracture-related Posterior Urethral Injuries : A Systematic Review [PDF]

, 2017
Peer ...
Elshout, Pieter Jan, Gonsalves, Michael, Kitrey, Noam D., Kuehhas, Franklin E., Lumen, Nicolaas, MacLennan, Steven, Sharma, Davendra M., Summerton, Duncan J., Veskimae, Erik, Yuan, Yuhong   +9 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Securing All intraVenous devices Effectively in hospitalised patients—the SAVE trial: study protocol for a multicentre randomised controlled trial [PDF]

, 2015
Introduction: Over 70% of all hospital admissions have a peripheral intravenous device (PIV) inserted; however, the failure rate of PIVs is unacceptably high, with up to 69% of these devices failing before treatment is complete.
Aukerman, Bausone-Gazda, Bhende, Bolton, Bregenzer, Callaghan, Campbell, Craig, Donlan, Ezingeard, Frey, Hadaway, Harwood, Hoffmann, Maki, Maki, Naimer, Needham, NSW Health, O'Grady, Rickard, Royer, Schears, Sheppard, Sherertz, Simonova, Singer, Smith, Smith, Van Gessel, Wallis, Webster, Wilkinson, Wilkinson, Wilkinson, Zingg   +35 more
core   +3 more sources

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Ultrasound guidance and risk for intravascular catheter-related infections among peripheral arterial catheters: a post-hoc analysis of two large randomized-controlled trials

Annals of Intensive Care, 2020
Background The impact on infectious risk of ultrasound guidance at insertion remains controversial in short-term arterial catheters (ACs). The present study investigated the association between ultrasound guidance (US) during AC insertion and major ...
Niccolò Buetti, Stéphane Ruckly, Jean-Christophe Lucet, Lila Bouadma, Carole Schwebel, Olivier Mimoz, Jean-François Timsit   +6 more
doaj   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Comparison of a tube core and Magill forceps for nasotracheal intubation: a randomised controlled trial

Trials, 2021
Background Magill forceps are frequently used to complete nasotracheal intubation (NTI). We aimed to identify a tube core that could conveniently facilitate the NTI process without using Magill forceps.
Rui Hu, Jing-Yi Niu, Li-Ning Wu, Hao Sun, Peng Sun, Jia-Ying Huang, Jun-Ma Yu   +6 more
doaj   +1 more source