Objective: Liddle syndrome (LS) is a rare autosomal dominant condition secondary to a gain-of-function mutation affecting the epithelial sodium channels (ENaCs) in the distal nephron.
Raven K. Brower, BS+5 more
doaj
Maternal chronic hypertension in women veterans
Abstract Objective To describe the prevalence of maternal chronic hypertension (MCH), assess how frequently blood pressure is controlled before pregnancy among those with MCH, and explore management practices for antihypertensive medications (AHM) during the pre‐pregnancy and pregnancy periods. Data Sources, Study Setting, and Study Design We conducted
Ceshae C. Harding+5 more
wiley +1 more source
22nd Annual Scientific Meeting of the Australasian Society of Nephrology [PDF]
This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and ...
Cavan, Susan+8 more
core +20 more sources
Calcineurin inhibition, cardiovascular consequences, vascular resistance, and potential responses
Abstract Aim To place the consequences of calcineurin inhibition in a cardiovascular context. Methods Literature review coupled with personal encounters. Results Calcineurin is a calcium‐binding and calmodulin‐binding protein that is conserved across evolution from yeast to mammals.
Friedrich C. Luft
wiley +1 more source
Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel [PDF]
Non-inactivating or slowly inactivating proton-gated cation channels are thought to play an important role in the perception of pain that accompanies tissue acidosis.
Bassilana, Frédéric+3 more
core +1 more source
Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARγ agonist pioglitazone [PDF]
PPARgamma-agonists enhance insulin sensitivity and improve glucose utilization in diabetic patients. Adverse effects of PPARgamma-agonists include volume retention and edema formation.
Amann, Kerstin+14 more
core +1 more source
In vitro determination of drug transfer from drug-coated balloons.
Drug-coated balloons are medical devices designed to locally deliver drug to diseased segments of the vessel wall. For these dosage forms, drug transfer to the vessel wall needs to be examined in detail, since drug released into the blood is cleared from
Anne Seidlitz+8 more
doaj +1 more source
Modulation of cyclic amp phosphodiesterase [PDF]
Modulation of kidney cyclic AMP pdase by diuretics and antihypertensives was studied. It was found that spironolactone activates pdase and that furosemide, ethacrynic acid, triameterine , quinethazone, metolazone, chlorothiazide, propranolol and ...
Fouquet, Gary
core +1 more source
The EuroHeart Failure Survey programme—a survey on the quality of care among patients with heart failure in Europe Part 2: treatment [PDF]
National surveys suggest that treatment of heart failure in daily practice differs from guidelines and is characterized by underuse of recommended medications.
Aguilar, JC+17 more
core +2 more sources
Observations in man and animals on the distribution and excretion of sodium and potassium [PDF]
The work described in the papers submitted was begun in 1950 when radioactive isotopes of sodium and potassium first became available for biological research.
Wilson, Graham Malcolm
core