Results 71 to 80 of about 4,579 (198)

Predicting, preventing and managing AMA discharges [PDF]

, 2009
Discharge against medical advice (AMA), in which the patient chooses to leave the hospital before the treating physician recommends discharge, continues to be a common and vexing problem, especially for hospitalists.
Bearelly, Dilip
core  

Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]

, 2015
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández, DE BLASI, Roberto Alberto, George, Dimopoulos, José Garnacho, Montero, José Miguel, Cisneros, Massimo, Antonelli, The MagicBullet study, Group   +6 more
core   +1 more source

Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures

British Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1802-1820, June 2025.
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan, Ciara Kirke, Leon O'Hagan, Frank Moriarty, Kevin D. Murphy, Laura J. Sahm, Cian O'Mahony, Emma J. Coyle, Stephen Byrne, Kieran Dalton   +9 more
wiley   +1 more source

Case Reports : Topiramate, a concealed cause of severe metabolic acidosis [PDF]

, 2017
Severe metabolic acidosis is common among critically ill patients, and topiramate is a rare cause that may fail recognition. We report a lady with acute encephalopathy who had severe non-anion gap metabolic acidosis that served as the clue leading to ...
Lovinger, Daniel, Ludwig, Kyle, Regunath, Hariharan, Schroeder, Ryan   +3 more
core   +1 more source

Development of the Japanese Anticholinergic Risk Scale: English translation of the Japanese article

Geriatrics &Gerontology International, Volume 25, Issue 1, Page 5-13, January 2025.
Background Anticholinergic burden, reflecting the cumulative impact of medications with anticholinergic properties, significantly predicts adverse drug reactions and geriatric syndromes in older adults. Although anticholinergic risk scales (ARS) have been developed and validated in various countries, none have been tailored specifically for Japan.
Fumihiro Mizokami, Tomohiro Mizuno, Rena Taguchi, Izumi Nasu, Sayaka Arai, Keiichiro Higashi, Ayaka Matsumoto, Miwako Kamei, Taro Kojima, Takayoshi Sakai, Yuuka Shibata, Yasushi Takeya, Masaki Mogi, Shizuo Yamada, Masahiro Akishita, Japanese Society of Geriatric Pharmacy Working Group on Japanese Anticholinergic Risk Scale   +15 more
wiley   +1 more source

Rare forms of nephrolithiasis

Pediatria i Medycyna Rodzinna, 2019
Inborn errors of metabolism that may lead to calculus formation within the urinary tract include: adenine phosphoribosyltransferase deficiency, xanthine oxidase deficiency, orotic aciduria (acidosis) type I and alkaptonuria.
Piotr Skrzypczyk, Małgorzata Pańczyk-Tomaszewska   +1 more
doaj   +1 more source

Ion channel expression in human melanoma samples. in silico identification and experimental validation of molecular targets [PDF]

, 2019
Expression of 328 ion channel genes was investigated, by in silico analysis, in 170 human melanoma samples and controls. Ninety-one members of this gene-family (i.e., about 28%) show a significant (p 0.90 and p 90% in most cases).
D’Arcangelo, Daniela, Facchiano, Antonio, Facchiano, Francesco, Giampietri, Claudia, Marchetti, Paolo, Scatozza, Francesca   +5 more
core   +1 more source

Combined Intratympanic and Systemic Steroid Therapy for Poor-Prognosis Sudden Sensorineural Hearing Loss [PDF]

Iranian Journal of Otorhinolaryngology, 2012
Introduction: The aim of this study was to evaluate the efficacy of combined intratympanic and systemic steroid therapy compared with systemic steroid therapy alone in idiopathic sudden sensorineural hearing loss (ISSNHL) patients with poor prognostic ...
Shima Arastou, Ardavan Tajedini, Pedram Borghei   +2 more
doaj   +2 more sources

Micro-RNAS that control myosin expression and myofiber identity [PDF]

, 2015
The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast fiber genes and activate slow fiber
Olson, Eric N., van Rooij, Eva
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton, Michael R. Gionfriddo, Gail B. Rattinger, Yuan Fang, Mia E. Lussier   +4 more
wiley   +1 more source