Results 51 to 60 of about 2,736 (181)

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

Interaction of Trypanosoma cruzi, Triatomines and the Microbiota of the Vectors—A Review

Microorganisms
This review summarizes the interactions between Trypanosoma cruzi, the etiologic agent of Chagas disease, its vectors, triatomines, and the diverse intestinal microbiota of triatomines, which includes mutualistic symbionts, and highlights open questions.
Günter A. Schaub
doaj   +1 more source

Behavior of triatomines (Hemiptera: Reduviidae) vectors of Chagas' disease: III. Influence of the number of matings on the fecundity and fertility of Panstrongylus megistus (Burm. 1835) in the laboratory

Memorias do Instituto Oswaldo Cruz, 1987
A study of the effect of mating in the fecundity and fertility of females of P. megistus fed on pigeon blood every 14 days, was carried out in the laboratory.
Marli Maria Lima, Pedro Jurberg, Josimar Ribeiro de Almeida   +2 more
doaj   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

DataTri, a database of American triatomine species occurrence [PDF]

Scientific Data, 2018
AbstractTrypanosoma cruzi, the causative agent of Chagas disease, is transmitted to mammals - including humans - by insect vectors of the subfamily Triatominae. We present the results of a compilation of triatomine occurrence and complementary ecological data that represents the most complete, integrated and updated database (DataTri)available on ...
Soledad Ceccarelli, Agustín Balsalobre, Paula Medone, María Eugenia Cano, Rodrigo Gurgel Gonçalves, D. Feliciangeli, Darío Vezzani, Cristina Wisnivesky‐Colli, David E. Gorla, Gerardo A. Martí, Jorge Rabinovich   +10 more
openaire   +3 more sources

A simplified method for sample collection and DNA isolation for polymerase chain reaction detection of Trypanosoma rangeli and Trypanosoma cruzi in triatomine vectors

Memorias do Instituto Oswaldo Cruz, 2000
Due to the overlapping distribution of Trypanosoma rangeli and T. cruzi in Central and South America, sharing several reservoirs and triatomine vectors, we herein describe a simple method to collect triatomine feces and hemolymph in filter paper for ...
Evandro MM Machado, Nelson J Alvarenga, Alvaro J Romanha, Edmundo C Grisard   +3 more
doaj   +1 more source

Synthesis and In Vitro Activity of Hypofuran B and Analogs Against Plasmodium Falciparum and Trypanosoma Cruzi

ChemMedChem, Volume 21, Issue 1, January 2026.
Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco, Jodieh Oliveira Santana Varejão, Isabela Penna Ceravolo, Victória Miranda Machado, Antoniana Ursine Krettli, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Felipe Terra Martins, Eduardo Jorge Pilau, Vinícius Ribeiro Montes, Markus Kohlhoff, Eduardo V. V. Varejão   +11 more
wiley   +1 more source

Successional and native forests predict the occurrence and infection status of Chagas disease vectors in Panama

Journal of Applied Ecology, Volume 63, Issue 1, January 2026.
Findings here show that successional forest predicts greater kissing bug infestation risk in palm trees, whereas native forest predicts lower kissing bug occurrence but greater infection with T. cruzi. These insights can guide land use planning towards vegetation management practices that help minimize T. cruzi transmission risks for rural communities.
Juliana Hoyos, Azael Saldaña, Sonia Altizer, Vanessa Pineda, Kadir Gonzalez, Jose E. Calzada, Raissa Nogueira de Brito, Susan Tanner, Daniel Mendieta, Alberto Cumbrera, Nicole L. Gottdenker   +10 more
wiley   +1 more source

Peridomestic structure, farming activity and triatomine infestation [PDF]

Parasite, 2006
The role of peridomestic structure and farming activity on triatomine infestation was studied on two vector species of Chagas disease (Triatoma pseudomaculata and T. brasiliensis) in Bahia State, northeastern Brazil. A randomly selected population issued from 136 farms was divided into four categories according to the householder activity.
Rego de, P. I., /Walter, Annie, Ferreira, A. J., Rangel, M., Girard Ferreira, E., /Noireau, François   +5 more
openaire   +4 more sources

Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease

Frontiers in Physiology
Introduction: Triatomines are vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Currently, there is no vaccine against this disease. Thus, control of the insect vector population is the main strategy available to reduce the number of
Mariana C. Costa, Carlos J. C. Moreira, Pedro Lagerblad de Oliveira, Pedro Lagerblad de Oliveira, José Juberg, Daniele Pereira de Castro, Daniele Pereira de Castro, Fernando Ariel Genta, Fernando Ariel Genta   +8 more
doaj   +1 more source