Results 1 to 10 of about 16,308 (224)

50 Years of Giese Reaction - a Personal View. [PDF]

Angew Chem Int Ed Engl
The Giese‐Reaction celebrates its 50. Birthday, it is a cyclic radical chain reaction centered around C,C‐bond formation in a three component synthesis. This minireview speaks about the birth of the name‐reaction, explains how the complete understanding of its reaction mechanism stimulates new methods in organic synthesis, and why it can proceed in ...
Spichty M, Zipse H, Majouri S, Fromm KM, Giese B.   +4 more
europepmc   +3 more sources

Neurotoxic Effects of Acute Tributyltin Exposure in Adult Zebrafish: Behavioral Impairments and Mechanistic Insights [PDF]

Metabolites
Background/Objectives: Tributyltin (TBT) remains a persistent aquatic contaminant with documented neurotoxic effects, yet the underlying mechanisms of its neurotoxicity remain poorly understood.
Qi Zheng, Nan Hong, Lin Liu, Cong Wang, Ruixi Gan, Di Xu, Junsong Wang   +6 more
doaj   +2 more sources

Synthesis and Evaluation of Radioiodinated [¹²⁵I]7-Iodo-5H-Pyrido[4,3-B]Indole ([¹²⁵I]CTAU) in Postmortem Human Alzheimer's Disease Brain. [PDF]

J Labelled Comp Radiopharm
[125I]CTAU, a new analog of [18F]T807, was found to be suitable for imaging tau protein in postmortem human Alzheimer's disease brain slices. [125I]CTAU may be among the smaller ring structures that bind to tau protein. ABSTRACT The aim of this study was to further understand the tau imaging agent, flortaucipir (T807), by making small modifications and
McNamara CC, Biju AP, Hipolito ELM, Nguyen NTB, Liang C, Mukherjee J.   +5 more
europepmc   +2 more sources

Tributyltin Alters Seric Bile Acid Pool Composition in Male Rats [PDF]

Toxics
Tributyltin (TBT), a recognized endocrine disruptor, is associated with metabolic diseases, including obesity, type 2 diabetes, non-alcoholic steatohepatitis, and osteoporosis.
Wenhuan Yao, Jinjiao Luan, Hui Li, Dong Cheng, Shibo Lv, Jiliang Si   +5 more
doaj   +2 more sources

Disruption of estrogen signaling by developmental exposure to BPA and TBT causes long term functional deficits in zebrafish retina [PDF]

Frontiers in Pharmacology
Bisphenol A (BPA) and tributyltin (TBT) are two endocrine disrupting compounds (EDC) that have opposite effects on estrogen signaling. BPA is an estrogen agonist that binds to all estrogen receptor types.
J. S. Jensen, J. S. Jensen, L. Ouellette, L. Ouellette, R. Harris, P. Owrang, V. P. Connaughton, V. P. Connaughton   +7 more
doaj   +2 more sources

Tributyltin (TBT) biodegradation induces oxidative stress of Cunninghamella echinulata [PDF]

International Biodeterioration and Biodegradation, 2016
Tributyltin (TBT) is one of the most deleterious compounds introduced into natural environment by humans. The ability of Cunninghamella echinulata to degrade tributyltin (TBT) (5 mg l-1) as well as the effect of the xenobiotic on fungal amino acids ...
Adrian Soboń, Rafał Szewczyk, Jerzy Długoński   +2 more
exaly   +3 more sources

Tributyltin and Zebrafish: Swimming in Dangerous Water [PDF]

Frontiers in Endocrinology, 2018
Zebrafish has been established as a reliable biological model with important insertion in academy (morphologic, biochemical, and pathophysiological studies) and pharmaceutical industry (toxicology and drug development) due to its molecular complexity and
Clemilson Berto-Júnior, Clemilson Berto-Júnior, Denise Pires de Carvalho, Denise Pires de Carvalho, Denise Pires de Carvalho, Paula Soares, Paula Soares, Paula Soares, Paula Soares, Leandro Miranda-Alves, Leandro Miranda-Alves, Leandro Miranda-Alves   +11 more
doaj   +4 more sources

Evaluation of the pollution pressures posed by groups of chemicals on British riverine invertebrate populations. [PDF]

Biol Rev Camb Philos Soc
ABSTRACT Globally, rivers receive a diverse range of chemicals, including metals, pesticides, persistent organic pollutants, petrochemicals, human and veterinary pharmaceuticals and personal care products. However, the extent to which these different chemical groups affect riverine invertebrate communities is not well defined.
Poyntz-Wright IP, Harrison XA, Tyler CR.
europepmc   +2 more sources

Tributyltin perturbs femoral cortical architecture and polar moment of inertia in rat

BMC Musculoskeletal Disorders, 2021
Background Tributyltin, a well-known endocrine disruptor, is widely used in agriculture and industry. Previous studies have shown that tributyltin could cause deleterious effects on bone health by impairing the adipo-osteogenic balance in bone marrow ...
Mingjun Li, Dong Cheng, Hui Li, Wenhuan Yao, Dongmei Guo, Shu’e Wang, Jiliang Si   +6 more
doaj   +1 more source

Tributyltin Exposure Is Associated With Recognition Memory Impairments, Alterations in Estrogen Receptor α Protein Levels, and Oxidative Stress in the Brain of Female Mice

Frontiers in Toxicology, 2021
Tributyltin (TBT) is a persistent organometallic pollutant widely used in several agricultural and industrial processes. TBT exposure is associated with various metabolic, reproductive, immune, and cardiovascular abnormalities.
Igor Ferraz da Silva, Eduardo Merlo, Charles S. Costa, Jones B. Graceli, Lívia C. M. Rodrigues   +4 more
doaj   +1 more source