Results 1 to 10 of about 359 (103)

Catch, Cut, or Block? Versatile 4-N-Derivatized Sialyl Glycosides for Influenza Virus Neuraminidase Detection and Purification. [PDF]

open access: yesAngew Chem Int Ed Engl
Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yuan Y   +6 more
europepmc   +3 more sources

Astatine-211-Towards In Vivo Stable Astatine-211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications. [PDF]

open access: yesMed Res Rev
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Müller M   +5 more
europepmc   +2 more sources

The action of trialkyltin compounds on mitochondrial respiration. The effect of pH. [PDF]

open access: yesBiochem J, 1974
1. Inhibition of 2,4-dinitrophenol-stimulated respiration by trialkyltins is dependent on the presence of Cl− in the assay medium and is only apparent at acid pH values. It appears to be a result of the Cl−–OH− exchange mediated by trialkyltins. 2. In a KCl medium at alkaline pH values, the maximum rate of respiration produced by uncouplers is further ...
Dawson AP, Selwyn MJ.
europepmc   +4 more sources

Organotin(IV) Alkoxides, Siloxides, and Related Stannoxanes. Characterisation and Thermogravimetric Studies. [PDF]

open access: yesChemistryOpen
The pendant‐arm ligand [2‐(CH2O)2CH]C6H4 (L) was successfully employed in the isolation of a limited series of organotin(IV) alkoxides and siloxides. A unique example of stannaboroxane was synthesised following a straight‐forward protocol. The thermogravimetric studies performed on the novel organotin(IV) siloxides reveal their potential application as
Penciu V, Bizo L, Varga RA, Someşan AA.
europepmc   +2 more sources

Trialkyltin Compounds Bind Retinoid X Receptor to Alter Human Placental Endocrine Functions [PDF]

open access: yesMolecular Endocrinology, 2005
AbstractRetinoid X receptor (RXR) is a nuclear receptor that plays important and multiple roles in mammalian development and homeostasis. We previously reported that, in human choriocarcinoma cells, tributyltin chloride and triphenyltin hydroxide, which are typical environmental contaminants and cause masculinization in female mollusks, are potent ...
Tsuyoshi Nakanishi   +2 more
exaly   +3 more sources

Catalytic ipso‐Nitration of Organosilanes Enabled by Electrophilic N‐Nitrosaccharin Reagent

open access: yesAngewandte Chemie, Volume 135, Issue 41, October 9, 2023., 2023
Deploying N‐nitrosaccharin reagents in combination with Lewis acid activation enables the facile, regio‐ and chemoselective nitration of (het)aryl silanes, allowing the introduction of nitro group under unprecedently mild conditions suitable for the late‐stage nitration of complex and polyfunctionalized molecules.
Ivan Mosiagin   +5 more
wiley   +2 more sources

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