Results 21 to 30 of about 906 (153)

Metal‐Catalyzed Carbonylation Reactions with CO2: An Update

ChemCatChem, Volume 15, Issue 20, October 20, 2023., 2023
Catalytic carbonylation with CO2: The latest updates on C1‐carbonylative homologation of carbon scaffolds by means of metal catalyzed fixation of CO2 are collected in the present Review article. Innovative catalytic systems, enabling technologies and mechanistic investigations are contributing to the current developments of this fascinating research ...
Riccardo Giovanelli, Giulio Bertuzzi, Marco Bandini   +2 more
wiley   +1 more source

Strukturchemische Aspekte der Organozinnchemie

CHIMIA, 1962
In a short survey the fundamental difference between organometallic and organometalloid chemistry is related to the reverse polarity of carbon-metal bonds in comparison with bonds between carbon and other elements.
G. J. M. van der Kerk, J. G. A. Luijten, M. J. Janssen   +2 more
doaj   +1 more source

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties

Journal of Chemistry, Volume 2022, Issue 1, 2022., 2022
Lead optimization represents the tedious process of fine‐tuning lead compounds from biologically active hits to suitable drug candidates for clinical trials. By chemically modifying a hit structure, an improved compound can be obtained in terms of activity, selectivity, and pharmacokinetic ADME (absorption, distribution, metabolism, and excretion ...
Kato Bredael, Silke Geurs, Dorien Clarisse, Karolien De Bosscher, Matthias D’hooghe, Andrea Trabocchi   +5 more
wiley   +1 more source

Synthesis, characterization and antifungal assessment of optically active bis-organotin compounds derived from (S)-BINOL diesters [PDF]

, 2019
Background: Organotin(IV) derivatives have appeared recently as potential biologically active metallopharmaceuticals exhibiting a variety of therapeutic activities.
Costantino, Andrea Rosana, Koll, Liliana Cristina, Mandolesi, Sandra Delia, Neudörfl, Jörg M., Ocampo, Romina Andrea, Svetaz, Laura Andrea, Zacchino, Susana Alicia Stella   +6 more
core   +1 more source

Size‐Induced Inversion of Selectivity in the Acylation of 1,2‐Diols

Chemistry – A European Journal, Volume 27, Issue 72, Page 18084-18092, December 23, 2021., 2021
The Lewis‐base catalyzed acylation of aromatic 1,2‐ethylenediols with anhydrides depends strongly on the size of the reagents and the π‐system of the diol. Steric effects have a larger impact on reactions of primary hydroxyl groups in the 1,2‐diol as well as the monoester than those of secondary hydroxyl groups. For sterically demanding anhydrides this
Stefanie Mayr, Hendrik Zipse
wiley   +1 more source

A versatile and an efficient synthesis of 5-​substituted-​1H-​tetrazoles [PDF]

, 2011
A simple, efficient and a versatile method for the synthesis of 5-​substituted-​1H-​tetrazoles by a [3+2]​-​cycloaddn. reaction of aryl nitriles with sodium azide in DMF using ZrOCl2·8 H2O as catalyst has been developed. The reactions work well at 100°C
Gowd Madhusudana Reddy Muthukur Bhoje, ., Pasha Mohamed Afzal, .   +1 more
core   +1 more source

The 2‐Pyridyl Problem: Challenging Nucleophiles in Cross‐Coupling Arylations

Angewandte Chemie, Volume 133, Issue 20, Page 11168-11191, May 10, 2021., 2021
This Review focuses on methods developed as solutions for the challenging coupling of 2‐pyridyl nucleophiles with (hetero)aryl electrophiles. The topic encompasses traditional cross‐coupling processes, modifications to the Suzuki–Miyaura coupling, as well as alternative nucleophilic reagents and recent developments in C−H activation.
Xinlan A. F. Cook, Antoine de Gombert, Janette McKnight, Loïc R. E. Pantaine, Michael C. Willis   +4 more
wiley   +1 more source

Sonochemical synthesis of bis(tri-n-butylstannyl) aromatic compounds via Barbier-like reactions [PDF]

, 2013
This paper reports a study of the synthesis of aryltri-n-butylstannanes via a sonochemical Barbier reaction of aryl- and heteroaryl bromides with bis(tri-n-butyltin) oxide (2) in THF.
Fidelibus, Pablo Martin, Gerbino, Darío César, Mandolesi, Sandra Delia, Ocampo, Romina Andrea, Podestá, Julio Cesar, Scoccia, Jimena   +5 more
core   +2 more sources

Synthesis and kinetic resolution of N-Boc-2-arylpiperidines [PDF]

, 2014
The chiral base n-BuLi/(-)-sparteine or n-BuLi/(+)-sparteine surrogate promotes kinetic resolution of N-Boc-2-arylpiperidines by asymmetric deprotonation. The enantioenriched starting material was recovered with yields 39-48% and ers up to 97:3.
Bailey, Barker, Becker, Beng, Beng, Binanzer, Coldham, Coldham, Cui, Daniele Leonori, Edward J. Cochrane, Faibish, Granander, Hardy, Harrison, Hesp, Horton, Hsieh, Hsieh, Iain Coldham, Kagan, Kessar, Krasnov, Kreituss, Li, Lorraine A. Hassall, Millet, O'Brien, Pellissier, Penning, Rutherford, Seel, Sheikh, Stead, Strohmann, Vo, Xiao, Xiao, Xiao, Zuo   +39 more
core   +1 more source

Organometallic catalysis for applications in radical chemistry and asymmetric synthesis [PDF]

, 2014
Two organometallic catalysis studies are presented. The first one deals with the development of a new catalytic agent based on the mixture of a hydride and an iron salt to trigger efficient radical cyclization processes.
Ateywiohrera, Augé, Baguley, Barbazanges, Broere, Ekomie, Fujita, Harrak, Inoue, Leca, Liu, Raducan, Renaud, Shibata, Short, Tanaka, Watson, Zuccaccia   +17 more
core   +3 more sources