Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
An integrated network toxicology, molecular docking, and in vitro validation approach was applied to identify TP53, ACTB, and CASP3 as key targets mediating trichloroethylene‐driven kidney carcinogenesis via aberrant signaling regulation. ABSTRACT Trichloroethylene (TCE), a pervasive environmental contaminant, is epidemiologically linked to kidney ...
Weijie Ma, Hui Cai
wiley +1 more source
Pollution Characteristics and Assessment of Carcinogenic and Non-Carcinogenic Risks of Volatile Halogenated Hydrocarbons in a Medium-Sized City of the Sichuan Basin, Southwest China. [PDF]
Wan X +6 more
europepmc +1 more source
ABSTRACT Introduction With an additional year of follow‐up compared with the previous report, this study presents the 27.2‐month efficacy and safety outcomes of the MajesTEC‐1 China cohort. Methods A total of 26 participants with triple‑class exposed relapsed/refractory multiple myeloma (TCE‐RRMM) received subcutaneous teclistamab 1.5 mg/kg weekly ...
Zhen Cai +20 more
wiley +1 more source
Heating Effect on the Liquid-Crystalline Octakis(hexylthio)zinc(II) Phthalocyanine Thin Film Sensor for the Detection of Chlorinated Hydrocarbon Vapors and Interaction Mechanism Analysis Using Density Functional Theory. [PDF]
Özer Z +5 more
europepmc +1 more source
Polyvinylidene Fluoride: Reaction Engineering and Applications
An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian +2 more
wiley +1 more source
Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde +6 more
wiley +2 more sources
Analyte Recovery of Volatile Organic Compounds: A Passive Sampling Analysis via Photothermal Desorption Compatible Diffusive Samplers. [PDF]
Shedd JS +4 more
europepmc +1 more source
In this work, a novel expanded graphite‐supported nano‐copper polydopamine composite was designed and synthesized. The procedure involved first modifying EG via a mussel‐inspired technique to deposit a polydopamine coating, after which Cu2+ ions were reduced to immobilize copper nanoparticles onto the EG‐PDA substrate.
Xingrong Liu, Fan Xia, Dietmar Auhl
wiley +1 more source
Draft metagenome-assembled genome sequence of a <i>Dehalogenimonas</i> species from an enriched consortium for complete trichloroethylene reductive dechlorination. [PDF]
Zhang L, Yang K, Zhang X.
europepmc +1 more source

