Results 121 to 130 of about 6,030 (221)

Clinical and immunological effects of adding cyclophosphamide to pomalidomide–dexamethasone in relapsed‐refractory multiple myeloma: The randomized MUKseven trial

open access: yesBritish Journal of Haematology, Volume 209, Issue 2, Page 557-568, August 2026.
Summary There is an ongoing need for accessible combination therapies for patients with relapsed‐refractory multiple myeloma (RRMM), alongside a growing interest in understanding their immunological effects, particularly on T‐cell populations. Myeloma UK (MUK) MUKseven (NCT02406222) was an academic, UK multicentre randomized controlled, open‐label ...
Andrew Hall   +14 more
wiley   +1 more source

Heritable pulmonary arterial hypertension: new genetic findings and environmental triggers. [PDF]

open access: yesSci Rep
Shaukat M   +15 more
europepmc   +1 more source

Constructed value of information with iterative scoring and parametric uncertainty to identify management‐relevant research priorities for a declining raptor species

open access: yesConservation Biology, Volume 40, Issue 4, August 2026.
Abstract Constructed value of information (CVoI) is an expert elicitation decision‐analytic tool used to prioritize sources of uncertainty based on their potential to improve decision outcomes if resolved. Despite increased application of CVoI, the robustness of CVoI prioritization of sources of uncertainty relative to differences in expert elicitation
Kristin P. Davis   +7 more
wiley   +1 more source

Liquid Chromatography–Tandem Mass Spectrometry Quantification of Diet‐Derived CYP2D6 Biomarkers for Clinical Phenotyping in Japanese Subjects

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The enzymatic activity of cytochrome P450 2D6 (CYP2D6) exhibits substantial interindividual variation, which influences drug efficacy and the risk of adverse drug reactions to various therapeutics. While current protocols for CYP2D6 genotyping or CYP2D6 phenotyping provide useful information, less invasive and simpler tools are desirable for ...
Masaki Kumondai   +11 more
wiley   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

open access: yesChemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati   +4 more
wiley   +1 more source

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