Results 81 to 90 of about 6,030 (221)
AtmosphereIn this study, the effects of various moisture pretreatment devices (MPDs) on the analytical process of trichloroethylene (TCE) and nitrous oxide (N2O), which are representative organic and inorganic compounds emitted from semiconductor industries, were ...
Da-Hyun Baek +4 more
doaj +1 more source
Trichloroethylene. II. Mechanism of carcinogenicity of trichloroethylene.
In vivo (Athens, Greece), 1999 The cancer inducing effect of trichloroethylene (TCE) was studied by various methods. DNA complexing activity and apoptosis inhibition were found to be the key elements of the carcinogenicity of TCE and its metabolites. The ability of TCE to interact with DNA was low, but its incorporation into the RNA and DNA of the brain, testis, pancreas, kidney ...
N, Motohashi, H, Nagashima, J, Molnár
openaire +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Carbon FutureElectrochemistry can provide a viable and sustainable way to treat water polluted by chlorinated volatile organic compounds. However, the removal and valorization of trichloroethylene (TCE) remains as a challenge due to the lack of suitable ...
Yuanzuo Gao +9 more
doaj +1 more source
Formation of Business‐Nonprofit Collaborations: A Matching Approach
Business Ethics, the Environment &Responsibility, EarlyView.ABSTRACT Business‐nonprofit collaborations are essential for addressing organizational and societal challenges, yet research has largely examined their formation from the perspective of a single partner rather than as a two‐sided process. In this study, we conceptualize collaboration formation as a dyadic matching process and examine two related ...
Andrea Rizzuni, Paola Garrone
wiley +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Cell Proliferation, EarlyView.Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen +7 more
wiley +1 more source
RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B
The FEBS Journal, EarlyView.The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal +4 more
wiley +1 more source
Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma
The FEBS Journal, EarlyView.IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture +3 more
wiley +1 more source
Temporal Evolution of Contaminant Mass Discharge: Effect of Source Remediation at Contaminated Sites
Groundwater Monitoring &Remediation, EarlyView.Abstract Contaminant mass discharge (CMD) is a key metric for evaluating remediation performance at contaminated sites posing a risk to groundwater. This study assesses temporal CMD trends and associated uncertainties using a geostatistical approach at a chlorinated solvent contaminated site following source zone remediation, supported by two decades ...
Anton Bøllingtoft +4 more
wiley +1 more source