Results 71 to 80 of about 64,045 (336)

Tunicate‐Inspired Carboxymethyl Cellulose Hydrogel Filler for Treating Age‐Associated Vocal Fold Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
The pyrogallol‐conjugated carboxymethylcellulose (CMC‐PG) hydrogel is applicated as a filler for the treatment of presbylaryngis, a vocal fold atrophy. CMC‐PG provides a bulking effect to the vocal folds. CMC‐PG is readily injectable and tissue adhesive, enabling sustained release of growth factor over long period.
Jihoon Jeon   +7 more
wiley   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

open access: yesAdvanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu   +30 more
wiley   +1 more source

Updates on molecular mechanisms in the development of branched trichome in Arabidopsis and nonbranched in cotton

open access: yesPlant Biotechnology Journal, 2019
Summary Trichomes are specialized epidermal cells and a vital plant organ that protect plants from various harms and provide valuable resources for plant development and use.
Zhi Wang, Zuoren Yang, Fuguang Li
semanticscholar   +1 more source

Interspecific differences in the larval performance of Pieris butterflies (Lepidoptera: Pieridae) are associated with differences in the glucosinolate profiles of host plants

open access: yes, 2019
The tremendous diversity of plants and herbivores has arisen from a coevolutionary relationship characterized by plant defense and herbivore counter adaptation. Pierid butterfly species feed on Brassicales plants that produce glucosinolates as a chemical
Hirai, M.   +6 more
core   +1 more source

The Mitochondrial Protein RESISTANCE to APHIDS 9 Interacts with S40 to Resist Aphid Infestation by Modulating Reactive Oxygen Species Homeostasis in Maize (Zea mays)

open access: yesAdvanced Science, EarlyView.
This study identifies the mitochondrial protein RTA9, a member of the Domain of Unknown Function 641 family, together with its partner S40, as key regulators of aphid resistance in maize. RTA9 promotes S40 degradation and modulates reactive oxygen species accumulation.
Chuanhong Wang   +12 more
wiley   +1 more source

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

open access: yesAdvanced Science, EarlyView.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng   +14 more
wiley   +1 more source

Scaling up from greenhouse resistance to fitness in the field for a host of an emerging forest disease. [PDF]

open access: yes, 2013
Forest systems are increasingly threatened by emergent, exotic diseases, yet management strategies for forest trees may be hindered by long generation times and scant background knowledge.
Dodd, Richard   +3 more
core   +1 more source

Secondary Metabolites Composition and Their Histochemical Localization in the Fruit of Piper malgassicum Papini, Palchetti, Gori and Rota Nodari (Piperaceae)

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The anatomy, histochemistry, and secondary metabolite composition were investigated on the drupes of Piper malgassicum, one of the components of the spice voatsiperifery pepper. The high amount of piperine recorded with high‐performance liquid chromatography with photodiode‐array detection analysis was localized with histochemistry mainly ...
Sara Falsini   +11 more
wiley   +1 more source

Micromorphological character expression of the hybrid Quercus × dysophylla and its parental species (Q. crassifolia and Q. crassipes)

open access: yesBotan‪ical Sciences, 2017
Background: Hybridization leads to individuals with atypical phenotypes, leading to taxonomic confusion when hybridizing populations are studied. Micromorphological characters may enable taxonomists to discriminate between parental and hybrid categories
Alfredo López-Caamal   +4 more
doaj   +1 more source

Arabidopsis JMJ29 is involved in trichome development by regulating the core trichome initiation gene GLABRA3.

open access: yesThe Plant Journal, 2020
Plant trichomes are large single cells organized in a regular pattern and play multiple biological functions. In Arabidopsis, trichome development is mainly governed by the core trichome initiation regulators including the R2R3 type MYB transcript factor
Fu-Yu Hung   +5 more
semanticscholar   +1 more source

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