Results 21 to 30 of about 2,354 (161)

The ventral epithelium of Trichoplax adhaerens deploys in distinct patterns cells that secrete digestive enzymes, mucus or diverse neuropeptides [PDF]

Biology Open, 2019
The disk-shaped millimeter-sized marine animal, Trichoplax adhaerens, is notable because of its small number of cell types and primitive mode of feeding.
Tatiana D. Mayorova, Katherine Hammar, Christine A. Winters, Thomas S. Reese, Carolyn L. Smith   +4 more
doaj   +2 more sources

Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens. [PDF]

Sci Rep, 2016
AbstractThe identification of genes encoding a p53 family member and an Mdm2 ortholog in the ancient placozoan Trichoplax adhaerens advocates for the evolutionary conservation of a pivotal stress-response pathway observed in all higher eukaryotes. Here, we recapitulate several key functionalities ascribed to this known interacting protein pair by ...
Siau JW, Coffill CR, Zhang WV, Tan YS, Hundt J, Lane D, Verma C, Ghadessy F.   +7 more
europepmc   +7 more sources

The enigmatic Placozoa part 2: Exploring evolutionary controversies and promising questions on earth and in space [PDF]

BioEssays, Volume 43, Issue 10, October 2021., 2021
The placozoan Trichoplax adhaerens has been bridging gaps between research discilplines like no other animal. As outlined in part 1, placozoans have been subject of hot evolutionary debates and placozoans have challenged some fundamental evolutionary ...
Humbert, Patrick O., Osigus, HJ, DeSalle, R, Schierwater, Bernd, Kamm, Kai, Rob DeSalle, Jens Hauslage, Kathrin Wysocki, Kvansakul, M, Hadrys, H, Humbert, PO, Blackstone, Neil W., Hauslage, Jens, Wysocki, K, Tjard Bergmann, Hauslage, J, Neil W. Blackstone, Marc Kvansakul, Wysocki, Kathrin, Bergmann, Tjard, Kai Kamm, Bergmann, T, DeSalle, Rob, Schierwater, B, Kamm, K, Hans‐Jürgen Osigus, Patrick O. Humbert, Heike Hadrys, Bernd Schierwater, Hadrys, Heike, Osigus, Hans‐Jürgen, Blackstone, NW, Kvansakul, Marc   +32 more
core   +3 more sources

Correction: Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of Trichoplax adhaerens. [PDF]

PLoS Biology
[This corrects the article DOI: 10.1371/journal.pbio.3001471.].
Angelo Fortunato, Alexis Fleming, Athena Aktipis, Carlo C Maley   +3 more
doaj   +2 more sources

Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses.

J Exp Biol, 2017
ABSTRACT Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the apparent absence of a true nervous system with electrical or chemical synapses. It glides along surfaces to find food, propelled by beating cilia
Senatore A, Reese TS, Smith CL.
europepmc   +4 more sources

Apicortin, a Putative Apicomplexan-Specific Protein, Is Present in Deep-Branching Opisthokonts [PDF]

Biology
Apicortin, a tubulin/microtubule-binding protein, was first described in 2009 as a protein characteristic of apicomplexans; it was found to be present in all Apicomplexa genomes already sequenced.
Ferenc Orosz
doaj   +2 more sources

Long-term dynamics of placozoan culture: emerging models for population and space biology [PDF]

Frontiers in Cell and Developmental Biology
As the simplest free-living animal, Trichoplax adhaerens (Placozoa) is emerging as a powerful paradigm to decipher molecular and cellular bases of behavior, enabling integrative studies at all levels of biological organization in the context of metazoan ...
Daria Y. Romanova, Alexander A. Povernov, Mikhail A. Nikitin, Simkha I. Borman, Yana A. Frank, Leonid L. Moroz, Leonid L. Moroz   +6 more
doaj   +2 more sources

Coordinated cellular behavior regulated by epinephrine neurotransmitters in the nerveless placozoa [PDF]

Nature Communications
Understanding how cells communicated before the evolution of nervous systems in early metazoans is key to unraveling the origins of multicellular life.
Minjun Jin, Wanqing Li, Zhongyu Ji, Guotao Di, Meng Yuan, Yifan Zhang, Yunsi Kang, Chengtian Zhao   +7 more
doaj   +2 more sources

Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms [PDF]

Nature Communications
Nucleocytoplasmic protein O-GlcNAcylation is a dynamic modification catalysed by O-GlcNAc transferase (OGT) and reversed by O-GlcNAc hydrolase (OGA), whose activities are regulated through largely unknown O-GlcNAc-dependent feedback mechanisms.
Sara Basse Hansen, Sergio G. Bartual, Huijie Yuan, Olawale G. Raimi, Andrii Gorelik, Andrew T. Ferenbach, Kristian Lytje, Jan Skov Pedersen, Taner Drace, Thomas Boesen, Daan M. F. van Aalten   +10 more
doaj   +3 more sources

Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor [PDF]

Communications Biology
Epsilon ionotropic glutamate receptors (iGluRs) are a recently defined clade of neurotransmitter receptors that are found in all major metazoan lineages that are distinct from α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, delta ...
Anhadvir Singh, Boris S. Zhorov, Luis A. Yanez-Guerra, Alessandra Aleotti, Chloe C. Koens, C. Defne Yanartas, Yunqi Song, Federico Javier Miguez Cabello, Derek Bowie, Adriano Senatore   +9 more
doaj   +2 more sources