Results 21 to 30 of about 8,907 (187)

Triclosan demonstrates synergic effect with amphotericin B and fluconazole and induces apoptosis-like cell death in Cryptococcus neoformans

Frontiers in Microbiology, 2016
Objectives: Cryptococcus neoformans is an opportunistic fungus that causes fatal meningoencephalitis especially in AIDS patients. There is an increasing need for discovery of new anti-cryptococcal drugs due to emergence of resistance cases in recent ...
Elaheh eMovahed, Grace Min Yi eTan, Komathy eMunusamy, Tee Cian eYeow, Sun Tee eTay, Won Fen eWong, Chung Yeng eLooi   +6 more
doaj   +1 more source

Do Different Sutures with Triclosan Have Different Antimicrobial Activities? A Pharmacodynamic Approach

Antibiotics, 2022
(1) Background: Three antimicrobial absorbable sutures have different triclosan (TS) loads, triclosan release kinetics and hydrolysis times. This in vitro study aims to analyse and compare their antimicrobial pharmacodynamics.
Frederic C. Daoud, Fatima M’Zali, Arnaud Zabala, Nicholas Moore, Anne-Marie Rogues   +4 more
doaj   +1 more source

Early-life triclosan exposure and parent-reported behavior problems in 8-year-old children

Environment International, 2019
Background: Triclosan exposure may decrease circulating thyroxine levels or cause neuron apoptosis, which in turn may adversely affect neurodevelopment.
Medina S. Jackson-Browne, George D. Papandonatos, Aimin Chen, Kimberly Yolton, Bruce P. Lanphear, Joseph M. Braun   +5 more
doaj   +1 more source

Susceptibility of MRSA to triclosan [PDF]

Journal of Antimicrobial Chemotherapy, 2002
Sir, Triclosan (2,4,4′-trichloro-2′-hydroxydiphenyl ether) is a broad-spectrum biocide that has been used for more than 30 years and can be found in a variety of household items, including toothpastes, cosmetics, antiseptic soaps, carpets, toys, floor cleaners, dishwashing detergents and even chopsticks.1,2 More recently it has been used in the ...
Z, Al-Doori, D, Morrison, G, Edwards, C, Gemmell   +3 more
openaire   +2 more sources

Profound perturbation induced by triclosan exposure in mouse gut microbiome: a less resilient microbial community with elevated antibiotic and metal resistomes

BMC Pharmacology and Toxicology, 2017
Background Environmental chemical-induced perturbations of gut microbiome are associated with a series of adverse health outcomes. The effects of triclosan on human health have been controversial in recent years.
Bei Gao, Pengcheng Tu, Xiaoming Bian, Liang Chi, Hongyu Ru, Kun Lu   +5 more
doaj   +1 more source

Functional screening for triclosan resistance in a wastewater metagenome and isolates of Escherichia coli and Enterococcus spp. from a large Canadian healthcare region.

PLoS ONE, 2019
The biocide triclosan is in many consumer products and is a frequent contaminant of wastewater (WW) such that there is concern that triclosan promotes resistance to important antibiotics.
Andrew Cameron, Ruth Barbieri, Ron Read, Deirdre Church, Emelia H Adator, Rahat Zaheer, Tim A McAllister   +6 more
doaj   +1 more source

Triclosan: an Instructive Tale [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT The Food and Drug Administration (FDA) recently released a final rule to ban triclosan and 18 other antimicrobial chemicals from soaps. We applaud this rule specifically because of the associated risks that triclosan poses to the spread of antibiotic resistance throughout the environment.
McNamara, Patrick J., Levy, Stuart B.
openaire   +2 more sources

Early life Triclosan exposure and child adiposity at 8 Years of age: a prospective cohort study

Environmental Health, 2018
Background Triclosan is an antimicrobial agent that may affect the gut microbiome and endocrine system to influence adiposity. However, little data from prospective studies examining prenatal and childhood exposures exist.
Geetika Kalloo, Antonia M. Calafat, Aimin Chen, Kimberly Yolton, Bruce P. Lanphear, Joseph M. Braun   +5 more
doaj   +1 more source

P38/TRHr-Dependent Regulation of TPO in Thyroid Cells Contributes to the Hypothyroidism of Triclosan-Treated Rats

Cellular Physiology and Biochemistry, 2018
Background/Aims: Triclosan, as an antimicrobial agent and a potential endocrine disruptor, has been used extensively in diverse products, resulting in widespread human exposure.
Pei Zhang, Min Yang, Li Zeng, Changjiang Liu   +3 more
doaj   +1 more source

Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis

Journal of Immunotoxicology, 2023
Triclosan is an anti-microbial chemical incorporated into products that are applied to the skin of healthcare workers. Exposure to triclosan has previously been shown to be associated with allergic disease in humans and impact the immune responses in ...
Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa M. Weatherly, Hillary L. Shane, Stacey E. Anderson   +5 more
doaj   +1 more source