Results 31 to 40 of about 29,679 (192)

The Price of Redo Mitral Valve Replacement: Determinants of Major Adverse Postoperative Events

Journal of Cardiovascular Development and Disease
Background: Redo mitral valve replacement is a high-risk operation in which early mortality alone may underestimate postoperative burden. We evaluated whether concomitant tricuspid valve repair independently increases major adverse postoperative events ...
Barış Timur, Zinar Apaydın
doaj   +1 more source

Choice of approaches for surgical correction of tricuspid pathology in patients with rheumatic multi-valvular heart disease

Heart Vessels and Transplantation, 2017
Objective: To analyze the results of surgical correction of patients with tricuspid pathology in rheumatic multi-valvular heart disease. Methods: We retrospectively analyzed outcomes of surgical correction of tricuspid valve disease in 292 patients ...
Hamidullah A. Abdumadzhidov, Hayrullah J. Buranov, Ilkhom K. Huzhakulov, Ikrom I. Mirhodzhaev, Sh. T. Artikov   +4 more
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Valve replacement for Ebstein’s anomaly of the tricuspid valve

The Journal of Thoracic and Cardiovascular Surgery, 1979
The role of valve replacement in the treatment of Ebstein's anomaly of the tricuspid valve remains controversial. Between 1965 and 1977, five patients with Ebstein's anomaly ranging in age from 11 to 57 years (mean 29) underwent tricuspid valve replacement in our institution. All of the patients were cyanotic but one, three were in Functional Class III,
E L, Bove, M M, Kirsh
openaire   +2 more sources

Safety and efficacy of total thoracoscopic surgery for patients with tricuspid regurgitation and reduced right ventricular function after left heart valves replacement: a retrospective comparative study

BMC Cardiovascular Disorders, 2023
Background Tricuspid valve surgery is the standard treatment for tricuspid valve disease refractory to pharmacologic therapy. However, patients with tricuspid regurgitation after previous left heart valves replacement with reduced right ventricular (RV ...
Zhiqin Lin, Zheng Xu, Xiujun Chen, Feng Lin, Liangwan Chen, Xiaofu Dai   +5 more
doaj   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Tricuspid valve surgery for acute infective endocarditis can be performed with very low operative mortalityCentral MessagePerspective

JTCVS Open
Objective: Tricuspid valve surgery historically has been perceived as having elevated operative risk, prompting the recent development of transcatheter therapies including aspiration vegetectomy for endocarditis.
Ali Darehzereshki, MD, J. Hunter Mehaffey, MD, MSc, J.W. Awori Hayanga, MD, MPH, Lawrence Wei, MD, Taylor D'etcheverry, PA-C, Luigi F. Lagazzi, MD, Vinay Badhwar, MD   +6 more
doaj   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Reoperation for isolated rheumatic tricuspid regurgitation

Journal of Cardiothoracic Surgery, 2018
Background The reoperation for isolated tricuspid regurgitation in rheumatic population is rare and still unclear and controversial because of the rarity of publications.
Younes Moutakiallah, Mahdi Aithoussa, Noureddine Atmani, Aniss Seghrouchni, Azeddine Moujahid, Abdedaïm Hatim, Iliyasse Asfalou, Zouhair Lakhal, Abdelatif Boulahya   +8 more
doaj   +1 more source