Results 221 to 230 of about 145,419 (376)

Depression resistant to tricyclic antidepressants. [PDF]

, 1988
Robert Hunter
openalex   +1 more source

Pyrroloquinoline Quinone Reprograms the Single‐Cell Landscape of Immune Aging in Hematopoietic Immune System

Aging Cell, EarlyView.
This study demonstrates that aging induces oxidative stress and inflammation in the hematopoietic immune system, resulting in immune homeostasis dysfunction, including alterations in B cells and hematopoietic stem cells, senescent cells (SnCs) accumulation, and senescence‐associated secretory phenotypes (SASPs) production. Notably, the study highlights
Xiuxing Liu, Chun Zhang, Jianjie Lv, Yidan Liu, Chenyang Gu, Yuehan Gao, Wen Ding, Hui Chen, Nanwei Xu, Hongbin Yin, Wenru Su, Zhuping Xu   +11 more
wiley   +1 more source

Antibacterial and Antifungal Properties of New Synthetic Tricyclic Flavonoids. [PDF]

Antibiotics (Basel)
Sarbu LG, Rosca I, Birsa ML.
europepmc   +1 more source

Tricyclic antidepressant pharmacology and therapeutic drug interactions updated

British Journal of Pharmacology, 2007
P. Gillman
semanticscholar   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β-Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D₂ Metabolite Methyl Ester. [PDF]

JACS Au
Xiao M, Shang Q, Pu L, Wang Z, Zhu L, Yang Z, Huang J.   +6 more
europepmc   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott, Videha Sharma, Jessica Keen, William Gerard Newman   +3 more
wiley   +1 more source

Fused Nitrogen Bridgehead N,O-Acetals as Versatile Scaffolds: Synthetic Strategies, Mechanism and Applications. [PDF]

Chemistry
Kouvelas AD, Kallitsakis MG, Lykakis IN.
europepmc   +1 more source

Trends in tricyclic antidepressant prescribing and poisoning in England and Wales 2016-2020. [PDF]

Br J Clin Pharmacol
Gray L, Beddard M, Jones S, Begum A, Azhar NB, Deslandes P, Coulson J, Bradberry S, Sandilands EA, Thanacoody RH, Ivory MO.   +10 more
europepmc   +1 more source

Validation of a transdiagnostic measure of fears of recurrence and progression about mental health conditions

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Fears of recurrence and progression (FORP) in people with mental health conditions are understudied despite predicting poorer psychological outcomes and increased rates of relapse. However, there are no well‐validated questionnaires that assess FORP in people with non‐psychotic conditions.
Daelin Coutts‐Bain, Louise Sharpe, Caroline Hunt   +2 more
wiley   +1 more source