Results 1 to 10 of about 39,692 (259)

Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice [PDF]

Journal of Mind and Medical Sciences, 2019
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Cornel Chiriță, Emil Ștefănescu, Cristina E. Zbârcea, Horațiu Mireșan, Simona Negreș, Diana C. Nuță, Carmen Limban, Rucsandra E. Dănciulescu Miulescu, Cristina D. Marineci   +8 more
doaj   +2 more sources

The Association between Antidepressant Medications and Coronary Heart Disease in Brazil: A Cross-sectional Analysis on the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil) [PDF]

Frontiers in Public Health, 2015
Background: Recent studies have highlighted associations between use of antidepressant medications and coronary heart disease (CHD). Tricyclic antidepressants are not recommended in patients with CHD as they may increase morbidity and mortality. However,
Andrew eKemp
doaj   +3 more sources

Survival after multiple in-hospital cardiac arrests due to severe amitriptyline poisoning– a case report [PDF]

International Journal of Emergency Medicine
Background Amitriptyline, a classic tricyclic antidepressant, can produce toxic effects ranging from mild antimuscarinic symptoms to severe cardiotoxicity due to sodium channel blockade. In severe cases, toxicity may rapidly progress to cardiac arrest if
Amanuel Dagabas Wakoya, Tadesse G. Asenabeto, Hawi D. Moti, Negash B. Bayu, Fenta Wondimneh, Abebe D. Ayinalem, Alemu B. Mesekere, Ayto A. Negash, Tiliksew A. Tesfaw   +8 more
doaj   +2 more sources

Analysis of the effects of a tricyclic antidepressant on secondary sleep disturbance induced by chronic pain in a preclinical model. [PDF]

PLoS One, 2020
Ito H, Takemura Y, Aoki Y, Hattori M, Horikawa H, Yamazaki M.   +5 more
europepmc   +2 more sources

Trends in tricyclic antidepressant prescribing and poisoning in England and Wales 2016-2020. [PDF]

Br J Clin Pharmacol
Gray L, Beddard M, Jones S, Begum A, Azhar NB, Deslandes P, Coulson J, Bradberry S, Sandilands EA, Thanacoody RH, Ivory MO.   +10 more
europepmc   +3 more sources

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson's disease. [PDF]

Psychopharmacology (Berl), 2022
Kamińska K, Lenda T, Konieczny J, Lorenc-Koci E.   +3 more
europepmc   +3 more sources

Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion

Journal of Pediatric Emergency and Intensive Care Medicine, 2021
Intoxication with tricyclic antidepressant drugs causes serious toxic findings even at low doses. Despite common use of the antidepressant drugs, there are no randomized controlled trials about treatments in tricyclic antidepressant drug intoxication ...
Ayyüce Ünlü, Mehmet Alakaya, Sadık Kaya, Ali Ertuğ Arslankoylu, Ali Korulmaz   +4 more
doaj   +1 more source

Amitriptyline induced Galactorrhea: A case report

Telangana Journal of Psychiatry, 2020
There have been a lot of documented cases of antipsychotic drug induced galactorrhea or non-puerperal lactation and isolated case reports of selective serotonin reuptake inhibitor induced galactorrhea.
Arijit Mondal, Aakanksha Malhotra, Sourav Bag, Soumi Ghosh   +3 more
doaj   +1 more source

Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]

, 2020
Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie, Gerlach, Ferdinand M, Glasziou, Paul P, Gonzalez-Gonzalez, Ana Isabel, Harder, Sebastian, Muth, Christiane, Nguyen, Truc Sophia, Pilz, Maximilian, Seide, Svenja E, Thomas, Elizabeth T   +9 more
core   +1 more source

Comparison of clinical manifestations of patients poisoned with tricyclic antidepressants alone or with benzodiazepine intoxication according to the dose of benzodiazepines

Journal of Research in Pharmacy Practice, 2022
Objective: Tricyclic antidepressants poisoning (TCA) is associated with cardiovascular complications, electrocardiographic abnormalities, and central nervous system toxicity.
Gholamali Dorooshi, Rasool Kermani, Ali Mohammad Sabzghabaee, Marjan Mansourian, Nastaran Eizadi-Mood   +4 more
doaj   +1 more source