Results 1 to 10 of about 21,297 (232)

Depression resistant to tricyclic antidepressants. [PDF]

BMJ, 1988
Robert Hunter
openalex   +5 more sources

Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion

Journal of Pediatric Emergency and Intensive Care Medicine, 2021
Intoxication with tricyclic antidepressant drugs causes serious toxic findings even at low doses. Despite common use of the antidepressant drugs, there are no randomized controlled trials about treatments in tricyclic antidepressant drug intoxication ...
Ayyüce Ünlü, Mehmet Alakaya, Sadık Kaya, Ali Ertuğ Arslankoylu, Ali Korulmaz   +4 more
doaj   +1 more source

Amitriptyline induced Galactorrhea: A case report

Telangana Journal of Psychiatry, 2020
There have been a lot of documented cases of antipsychotic drug induced galactorrhea or non-puerperal lactation and isolated case reports of selective serotonin reuptake inhibitor induced galactorrhea.
Arijit Mondal, Aakanksha Malhotra, Sourav Bag, Soumi Ghosh   +3 more
doaj   +1 more source

Comparison of clinical manifestations of patients poisoned with tricyclic antidepressants alone or with benzodiazepine intoxication according to the dose of benzodiazepines

Journal of Research in Pharmacy Practice, 2022
Objective: Tricyclic antidepressants poisoning (TCA) is associated with cardiovascular complications, electrocardiographic abnormalities, and central nervous system toxicity.
Gholamali Dorooshi, Rasool Kermani, Ali Mohammad Sabzghabaee, Marjan Mansourian, Nastaran Eizadi-Mood   +4 more
doaj   +1 more source

Development of Sodium Sulfate Induced Water Based Dispersive Liquid–Liquid Microextraction for the Extraction of Four Tricyclic Antidepressants in Urine Samples Prior to Their Determination by Gas Chromatography–Mass Spectrometry [PDF]

Pharmaceutical Sciences, 2021
Background: Because of the narrow therapeutic range of tricyclic antidepressant drugs, their determination in biological samples is of great importance. In this work, a fast and environment friendly sample pretreatment method based on a dispersive liquid–
Ali Mohebi, Mir Ali Farajzadeh, Abolghasem Jouyban, Mahboob Nemati, Mohammad Reza Afshar Mogaddam   +4 more
doaj   +1 more source

Chewing the fat: A case report on intravenous lipid emulsion to reverse cardiotoxicity from intentional amitriptyline overdose.

African Journal of Emergency Medicine, 2012
Introduction: Tricyclic antidepressant overdoses are a common presenting problem to emergency centres in South Africa. Case history: A 20-year-old female was brought to the emergency centre in status epilepticus due to tricyclic antidepressant toxicity ...
J. Hellig, I. Von Watzdorf, S. Lahri, K. Vallabh, R.L. Allgaier   +4 more
doaj   +1 more source

THE RADIOIMMUNOASSAY OF TRICYCLIC ANTIDEPRESSANTS [PDF]

British Journal of Clinical Pharmacology, 1976
An antiserum to nortriptyline has been produced in a sheep against a nortriptyline‐bovine serum albumin conjugate. The conjugate was prepared using the reagent N‐(4‐bromobutyl) phthalimide followed by a carbodiimide reaction to link the hapten to the carrier protein.
G W Aherne, E. M. Piall, Vincent Marks
openaire   +2 more sources

Alterações eletrocardiográficas na intoxicação aguda por antidepressivo tricíclico e suas implicações clínicas

Medicina, 2010
Introdução: A intoxicação aguda por antidepressivos tricíclicos é comum nas salas de emergência. Anormalidades no eletrocardiograma de 12 derivações (ECG) são associadas a este tipo de intoxicação, com implicações diagnósticas e prognósticas.
Carlos H. Miranda, Paula M. Luciano, Andrés R. P. Riera, Antônio Pazin Filho   +3 more
doaj   +1 more source

Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation

Cell Communication and Signaling, 2023
Background Idiosyncratic drug-induced liver injury (IDILI) is common in hepatology practices and, in some cases, lethal. Increasing evidence show that tricyclic antidepressants (TCAs) can induce IDILI in clinical applications but the underlying ...
Wenqing Mu, Guang Xu, Zhilei Wang, Qiang Li, Siqiao Sun, Qin Qin, Zhiyong Li, Wei Shi, Wenzhang Dai, Xiaoyan Zhan, Jiabo Wang, Zhaofang Bai, Xiaohe Xiao   +12 more
doaj   +1 more source

Antidepressant sales and the risk for alcohol-related and non-alcohol-related suicide in Finland--an individual-level population study.

PLoS ONE, 2014
ObjectivesA marked decline in suicide rates has co-occurred with increased antidepressant sales in several countries but the causal connection between the trends remains debated.
Heta Moustgaard, Kaisla Joutsenniemi, Mikko Myrskylä, Pekka Martikainen   +3 more
doaj   +1 more source