Results 81 to 90 of about 2,600,662 (296)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
LHCb trigger streams optimization
, 2017 The LHCb experiment stores around $10^{11}$ collision events per year. A typical physics analysis deals with a final sample of up to $10^7$ events. Event preselection algorithms (lines) are used for data reduction.
Derkach, D. +6 more
core +1 more source
TechnologiesIt is demonstrated that neuromorphic materials designed for computational tasks can be effectively implemented by drawing an analogy with trigger-based systems built upon classical binary elements.
Dina Shaltykova +4 more
doaj +1 more source
Bibliometric analysis of triggers on environmental stress among medical and health sciences students at the university [PDF]
Scripta MedicaContinuing to improve services to students while studying on campus, lecturers and all elements at the university need information about triggers of environmental stress among medical and health sciences students.
Kurniawan Wawan +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Journal of Clinical Oncology, 2004 VOLUME 22 䡠 NUMBER 17 䡠 SEPTEMBER 1 2004 J OURNAL OF C LINICAL O NCOLOGY T H E A R T O F O N C O L O G Y: When the Tumor Is Not the Target Pulling the Trigger Frank L. Meyskens Jr and John H. Fetting From the Comprehensive Cancer Center, University of California Irvine, Orange, CA; and The Johns Hopkins Oncology Center, Baltimore, MD.
Meyskens, Frank L, Jr, Fetting, John H
openaire +3 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source