Results 111 to 120 of about 1,583,927 (302)
Frontiers in Sports and Active LivingIntroductionShort-track speed skating (short track) is an Olympic sport characterized by a specific body position and counterclockwise movement on the track.
Mariusz Konieczny +7 more
doaj +1 more source
A Reply to “Option Value of Harvesting†Revisited (The Comment) [PDF]
Li’s results (1998) are correct and robust. The Comment offers an interesting perspective from real-options theory, albeit misguided--from a resource-economics point of view.
Li, Eric A.L.
core +1 more source
A broader perspective on point of view: logophoricity in Ogonoid languages [PDF]
, 2006 Logophoric marking in the Ogonoid family (Benue-Congo, Niger-Congo) differs significantly from most other logophoric reference systems in that these languages employ distinct verbal suffixes in logophoric domains, in addition to regular participant ...
Bond, Oliver
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Pengaruh Penambahan Core Stability Exercise Pada Muscle Energy Technique Terhadap Penurunan Nyeri Myofacial Trigger Point Upper Trapezius Pada Pembatik PT Danar Hadi [PDF]
, 2015 Background: Myofascial Trigger Point Syndrome (MTPS) is one of the conditions causing pain originated from nerves, bones and joints. MTPS itself is a syndrome arises due to the affectivity of one or more trigger points in the muscle fibers.
, Isnaini Herawati, S.Fis.,Ftr.,M.Sc +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source