Results 151 to 160 of about 229,067 (324)

Household Income, Maternal Allostatic Load During Pregnancy, and Offspring With Autism Spectrum Disorders

open access: yesAutism Research, EarlyView.
ABSTRACT Relative maternal poverty is a suggested social determinant of autism spectrum disorders (ASDs) in offspring; however, this association may be confounded by the maternal broader autism phenotype (BAP). The biological mechanisms underlying this association are largely understudied.
Shuhei Terada   +20 more
wiley   +1 more source

Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice

open access: yesJournal of Lipid Research, 2012
Phosphatidylethanolamine is an important inner-leaflet phospholipid, and CTP:phosphoethanolamine cytidylyltransferase-Pcyt2 acts as the main regulator of the de novo phosphatidylethanolamine synthesis from ethanolamine and diacylglycerol.
Ratnesh Kumar Singh   +3 more
doaj  

The role of Moringa oleifera in the development of alternative biofuels, under the concept of an integral one‐tree biorefinery: A minireview

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The Moringa oleifera oil tree is commonly known as the ‘tree of life’ or the ‘miracle tree’ owing to its multiple benefits for humans. The different parts that make up this tree (leaves, seeds and bark) have been used to treat various ailments, diseases and wounds. However, in recent years this tree is being used by the scientific community to
J. L. Aleman‐Ramirez   +4 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang   +7 more
wiley   +1 more source

Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients

open access: yesJournal of Lipid Research, 2002
Sirolimus (Rapammune®, rapamycin, RAPA) is a potent immunosuppressive drug that reduces renal transplant rejection. Hyperlipidemia is a significant side effect of sirolimus treatment, and frequently leads to cardiovascular disease.
Joel D. Morrisett   +9 more
doaj  

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

open access: yesBMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah   +9 more
wiley   +1 more source

A Concept Formula With Large, Milk Phospholipid‐Coated Lipid Droplets Enriched With Milk Fat Decreases Palmitic Acid and Calcium Levels in Stools of Healthy, Term Infants

open access: yesEuropean Journal of Lipid Science and Technology, Volume 124, Issue 12, December 2022., 2022
Less formation of calcium soaps in infant formula containing (more) sn‐2 palmitate (PA) Top: pathway of sn‐1,3 PA, Bottom: pathway of sn‐2 PA Abstract This study evaluates the impact of an infant formula comprising large, dairy milk phospholipid‐coated lipid droplets containing a vegetable‐dairy lipid mixture (Concept‐Mix) with 6% of fatty acid (FA) as
Bert J. M. van de Heijning   +4 more
wiley   +1 more source

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