Results 21 to 30 of about 517,171 (297)

Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder

Orphanet Journal of Rare Diseases, 2019
Triglyceride deposit cardiomyovasculopathy (TGCV) is a phenotype primarily reported in patients carrying genetic mutations in PNPLA2 encoding adipose triglyceride lipase (ATGL) which releases long chain fatty acid (LCFA) as a major energy source by the ...
Ming Li, Ken-ichi Hirano, Yoshihiko Ikeda, Masahiro Higashi, Chikako Hashimoto, Bo Zhang, Junji Kozawa, Koichiro Sugimura, Hideyuki Miyauchi, Akira Suzuki, Yasuhiro Hara, Atsuko Takagi, Yasuyuki Ikeda, Kazuhiro Kobayashi, Yoshiaki Futsukaichi, Nobuhiro Zaima, Satoshi Yamaguchi, Rojeet Shrestha, Hiroshi Nakamura, Katsuhiro Kawaguchi, Eiryu Sai, Shu-Ping Hui, Yusuke Nakano, Akinori Sawamura, Tohru Inaba, Yasuhiko Sakata, Yoko Yasui, Yasuyuki Nagasawa, Shintaro Kinugawa, Kazunori Shimada, Sohsuke Yamada, Hiroyuki Hao, Daisaku Nakatani, Tomomi Ide, Tetsuya Amano, Hiroaki Naito, Hironori Nagasaka, Kunihisa Kobayashi, on behalf of the Japan TGCV study group   +38 more
doaj   +1 more source

Study of lipid profile for psoriatic patients in AL-Anbar governorate. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
Psoriasis is a chronic inflammatory skin condition which affects approximately 1-3% of the world's population (1). It appears as red plaques covered with silvery scale that flakes away from the skin.Psoriatic plaques are often found on the elbows, scalp ...
Wajeeh Y. Mohammed, Abdullah S. Al-Hasan, Ausama A. Faisal   +2 more
doaj   +1 more source

Triglycerides and Cardiovascular Risk [PDF]

Current Cardiology Reviews, 2009
In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma ...
Harchaoui, K. E. L., Visser, M. E., Kastelein, J. J. P., Stroes, E. S., Dallinga-Thie, G. M.   +4 more
openaire   +2 more sources

Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy. [PDF]

, 2003
BACKGROUND: Triglyceride concentrations are raised in pregnancy and are considered a key fetal fuel. Several gene variants are known to alter triglyceride concentrations, including those in the Apolipoprotein E (ApoE), Lipoprotein Lipase (LPL), and most ...
Andrew T Hattersley, Beatrice Knight, Kirsten J Ward, Ward Kirsten J, Knight Beatrice, Hattersley, Andrew T, Ward, Kirsten J, Maurice B Salzmann, Timothy M Frayling, Frayling, Timothy M, Beverley Shields, Shields, Beverley, Salzmann Maurice B, Hattersley Andrew T, Shields Beverley, Frayling Timothy M, Knight, Beatrice, Salzmann, Maurice B   +17 more
core   +1 more source

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance. [PDF]

, 2011
OBJECTIVE: The causal nature of associations between circulating triglycerides, insulin resistance, and type 2 diabetes is unclear. We aimed to use Mendelian randomization to test the hypothesis that raised circulating triglyceride levels causally ...
Gaunt, TR, Weedon, Michael N., De Silva, N. Maneka G., Weedon, MN, Luan, Jian'an, Harbord, Roger M., Harbord, Roger M, Ward, Kirsten J, Luan, J, Smith, GD, N. Maneka G. De Silva, Morris, Andrew D, Morris, Andrew D., Gaunt, Tom, Ebrahim, S, Ward, KJ, Claudia Langenberg, Knight, Beatrice A., Donnelly, Louise A, Beverley Shields, McCarthy, Mark I, Shah Ebrahim, De Silva, N. Maneka G, Palmer, Colin N A, Timothy M. Frayling, Ebrahim, Shah, Tom Gaunt, Debbie A. Lawlor, Rachel M. Freathy, Sandhu, MS, Ebrahim, Shah B J, Sandhu, Manjinder S., Hattersley, Andrew T., Harbord, RM, Beatrice A. Knight, Hattersley, Andrew T, Smith, George Davey, Palmer, Colin N. A., Knight, Beatrice A, Lawlor, DA, Louise A. Donnelly, Knight, BA, Langenberg, C, Freathy, RM, Roger M. Harbord, Freathy, Rachel M, Andrew T. Hattersley, Weedon, Michael N, Hattersley, AT, Palmer, CN, McCarthy, MI, Michael N. Weedon, Palmer, Tom M, Sandhu, Manjinder S, Palmer, CNA, Shields, B, Lawlor, Debbie A, Andrew D. Morris, Langenberg, Claudia, Shields, Beverley, De Silva, N Maneka G, Ward, Kirsten J., Mark I. McCarthy, Palmer, Colin NA, Donnelly, LA, De Silva, NM, Davey Smith, G, Frayling, Timothy M., Wareham, N, Tom M. Palmer, Gaunt, T, Nicholas Wareham, Morris, AD, Jian'an Luan, Lawlor, D, Manjinder S. Sandhu, Lawlor, Debbie A., Wareham, Nicholas, McCarthy, Mark I., Freathy, Rachel M., Palmer, TM, Frayling, Timothy M, Kirsten J. Ward, Donnelly, Louise A., George Davey Smith, Palmer, Tom M., De Silva, N M G, Colin N.A. Palmer, Frayling, TM, Palmer, Colin N. A.; id_orcid   +89 more
core   +1 more source

Knockdown of lnc-KCNC3-3:1 Alleviates the Development of Atherosclerosis via Downregulation of JAK1/STAT3 Signaling Pathway

Frontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is a major cause of coronary artery disease (CAD), and CAD is one of the main causes leading to death in most countries. It has been reported that lncRNAs play important roles in the development of atherosclerosis; thus, we ...
Limin Sun, Xin He, Tao Zhang, Guizhou Tao, Xin Wang   +4 more
doaj   +1 more source

Triglyceride-Tethered Membrane Lipase Sensor

, 2023
Sensors that can quickly measure the lipase activity from biological samples are useful in enzyme production and medical diagnostics. However, current lipase sensors have limitations such as requiring fluorescent labels, pH control of buffer vehicles, or
Charles G. Cranfield (3191211), Upeksha Mirissa Lankage (17343473), Samara Bridge (17343476), Stephen A. Holt (283442), Bruce Cornell (3191205)   +4 more
core   +1 more source

Triglyceride-glucose index variability and incident cardiovascular disease: a prospective cohort study

, 2022
Background: Recent studies have suggested that triglyceride-glucose (TyG) index is an independent predictor of cardiovascular disease (CVD). However, the impact of long-term visit-to-visit variability in TyG index on the risk of CVD is not known.
X Guo (1378956), A Wang (4241158), F Qian (9854591), S Chen (5107745), Xia Li (9484709), S Wu (6794345), H Li (100694), P Wang (1542061), Y Zuo (9878198), X Tian (7942073)   +9 more
core   +1 more source

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

Lipase-modified pH-responsive microgel-based optical device for triglyceride sensing [PDF]

, 2015
Lipase-modified pH-responsive poly(N-isopropylacrylamide)-based microgels were synthesized. An optical device was subsequently fabricated by sandwiching the enzyme loaded responsive microgels between two thin Au layers, and their response to triolein, a ...
Zhang, Qiang M., Berg, Darren, Mugo, Samuel M., Serpe, Michael J.   +3 more
core   +1 more source