Results 251 to 260 of about 694,820 (288)
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Annals of Internal Medicine, 1976
Excerpt To the editor: According to the recent paper of Dr. Cattran and colleagues (1), peritoneal dialysis leads to more severe and sustained hypertriglyceridemia than hemodialysis.
D G, Oreopoulos +3 more
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Excerpt To the editor: According to the recent paper of Dr. Cattran and colleagues (1), peritoneal dialysis leads to more severe and sustained hypertriglyceridemia than hemodialysis.
D G, Oreopoulos +3 more
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Triglyceride-Rich Lipoproteins
Cardiology Clinics, 2018Plasma triglyceride levels are causally related to an increased risk of cardiovascular disease. Here, the authors summarize their understanding of triglyceride-rich lipoprotein metabolism, previous and newly identified regulators, and their relevance as candidate targets for therapeutic intervention.
Maaike, Kockx, Leonard, Kritharides
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Triglyceride Deposit Cardiomyovasculopathy
New England Journal of Medicine, 2008Triglyceride deposit cardiomyovasculopathy (TGCV) is a novel disease concept we found in Japanese cardiac transplant candidates in 2008. Probands carried mutations in the PNPLA2 gene encoding adipose triglyceride lipase (ATGL). ATGL is the major enzyme that catalyzes the initial rate-limiting step of intracellular triglyceride hydrolysis to release ...
Ken-ichi, Hirano +4 more
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Bioorganic & Medicinal Chemistry, 2014
This review is the first attempt at systematization of the literature data on the structures and activities of triglyceride-lowering agents which used in medical practice or are in development. The effects and mechanisms of action of statins, squalene synthase inhibitors, fibrates, PPARα and PPARα/γ agonists, nicotinic acid, omega-3 fatty acids and ...
Nariman F, Salakhutdinov, Sergey S, Laev
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This review is the first attempt at systematization of the literature data on the structures and activities of triglyceride-lowering agents which used in medical practice or are in development. The effects and mechanisms of action of statins, squalene synthase inhibitors, fibrates, PPARα and PPARα/γ agonists, nicotinic acid, omega-3 fatty acids and ...
Nariman F, Salakhutdinov, Sergey S, Laev
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Xenobiotic triglyceride formation
Xenobiotica, 19801. When 3-phenoxy[14C]benzoic acid was dosed orally (0.76 mg/kg) to rats, 1--3% of the administered radioactivity was found in the skin four days after dosing. Approximately 90% of this residue was unchanged 3-phenoxybenzoate, 10% was a neutral compound. 2. The residue in the skins of rats dosed with 193 mg of 3-phenoxybenzoic acid over 7 days (c.
J V, Crayford, D H, Hutson
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Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia
Nature Reviews Cardiology, 2022J. Borén +3 more
semanticscholar +1 more source
Trends in Cardiovascular Medicine, 2017
Elevated cholesterol levels are clearly independently associated with adverse cardiovascular events. Another class of lipid particles, triglycerides, is also abundant in the human body and has been found in atherosclerotic plaques. Recent observational studies have demonstrated an association between elevated triglyceride levels and increased risk for ...
Philipp, Wiesner, Karol E, Watson
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Elevated cholesterol levels are clearly independently associated with adverse cardiovascular events. Another class of lipid particles, triglycerides, is also abundant in the human body and has been found in atherosclerotic plaques. Recent observational studies have demonstrated an association between elevated triglyceride levels and increased risk for ...
Philipp, Wiesner, Karol E, Watson
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Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels
Science, 2007R. Saxena +66 more
semanticscholar +1 more source
Cardiology, 1991
Nicotinic acid and clofibrate derivatives are the main triglyceride-metabolism-affecting drugs. Nicotinic acid and its derivatives block adipose tissue lipolysis thus reducing the FFA flux of free fatty acids to the liver and the synthesis of very-low-density lipoproteins (VLDL). VLDL removal rate is also enhanced.
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Nicotinic acid and clofibrate derivatives are the main triglyceride-metabolism-affecting drugs. Nicotinic acid and its derivatives block adipose tissue lipolysis thus reducing the FFA flux of free fatty acids to the liver and the synthesis of very-low-density lipoproteins (VLDL). VLDL removal rate is also enhanced.
openaire +2 more sources