Results 351 to 360 of about 844,308 (381)

Triglyceride-lowering agents

Bioorganic & Medicinal Chemistry, 2014
This review is the first attempt at systematization of the literature data on the structures and activities of triglyceride-lowering agents which used in medical practice or are in development. The effects and mechanisms of action of statins, squalene synthase inhibitors, fibrates, PPARα and PPARα/γ agonists, nicotinic acid, omega-3 fatty acids and ...
Nariman F, Salakhutdinov, Sergey S, Laev
openaire   +2 more sources

Xenobiotic triglyceride formation

Xenobiotica, 1980
1. When 3-phenoxy[14C]benzoic acid was dosed orally (0.76 mg/kg) to rats, 1--3% of the administered radioactivity was found in the skin four days after dosing. Approximately 90% of this residue was unchanged 3-phenoxybenzoate, 10% was a neutral compound. 2. The residue in the skins of rats dosed with 193 mg of 3-phenoxybenzoic acid over 7 days (c.
J V, Crayford, D H, Hutson
openaire   +2 more sources

Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia

Nature Reviews Cardiology, 2022
J. Borén, M. Taskinen, Elias Björnson, C. Packard   +3 more
semanticscholar   +1 more source

Triglycerides: A reappraisal

Trends in Cardiovascular Medicine, 2017
Elevated cholesterol levels are clearly independently associated with adverse cardiovascular events. Another class of lipid particles, triglycerides, is also abundant in the human body and has been found in atherosclerotic plaques. Recent observational studies have demonstrated an association between elevated triglyceride levels and increased risk for ...
Philipp, Wiesner, Karol E, Watson
openaire   +2 more sources

Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels

Science, 2007
R. Saxena, B. Voight, V. Lyssenko, N. Burtt, P. D. de Bakker, Hong Chen, J. Roix, S. Kathiresan, J. Hirschhorn, M. Daly, T. Hughes, L. Groop, D. Altshuler, P. Almgren, J. Florez, Joanne M. Meyer, K. Ardlie, K. Bengtsson Boström, B. Isomaa, G. Lettre, U. Lindblad, H. Lyon, O. Melander, C. Newton‐Cheh, P. Nilsson, M. Orho-Melander, L. Råstam, Elizabeth K. Speliotes, M. Taskinen, T. Tuomi, C. Guiducci, A. Berglund, J. Carlson, Lauren Gianniny, Rachel Hackett, Liselotte Hall, J. Holmkvist, E. Laurila, M. Sjögren, M. Sterner, Aarti Surti, M. Svensson, M. Svensson, R. Tewhey, B. Blumenstiel, Melissa Parkin, M. DeFelice, Rachel Barry, W. Brodeur, J. Camarata, Na-Yu Chia, M. Fava, J. Gibbons, B. Handsaker, C. Healy, K. Nguyen, C. Gates, C. Sougnez, D. Gage, Marcia M. Nizzari, S. Gabriel, G. Chirn, Qicheng Ma, H. Parikh, D. Richardson, D. Ricke, S. Purcell   +66 more
semanticscholar   +1 more source

Drugs Affecting Triglycerides

Cardiology, 1991
Nicotinic acid and clofibrate derivatives are the main triglyceride-metabolism-affecting drugs. Nicotinic acid and its derivatives block adipose tissue lipolysis thus reducing the FFA flux of free fatty acids to the liver and the synthesis of very-low-density lipoproteins (VLDL). VLDL removal rate is also enhanced.
openaire   +2 more sources

Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase

Science, 2004
R. Zimmermann, J. Strauss, G. Haemmerle, Gabriele Schoiswohl, R. Birner‐Gruenberger, M. Riederer, A. Lass, Georg Neuberger, F. Eisenhaber, A. Hermetter, R. Zechner   +10 more
semanticscholar   +1 more source

Medium Chain Triglycerides

Gastroenterology, 1967
openaire   +2 more sources

Brown adipose tissue activity controls triglyceride clearance

Nature Medicine, 2011
A. Bartelt, Oliver T. Bruns, R. Reimer, H. Hohenberg, H. Ittrich, K. Peldschus, M. Kaul, U. Tromsdorf, H. Weller, C. Waurisch, A. Eychmüller, P. Gordts, F. Rinninger, Karoline Bruegelmann, Barbara Freund, P. Nielsen, M. Merkel, J. Heeren   +17 more
semanticscholar   +1 more source

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population.

American Journal of Physiology. Endocrinology and Metabolism, 2005
L. Szczepaniak, P. Nurenberg, D. Leonard, J. Browning, J. Reingold, S. Grundy, H. Hobbs, R. Dobbins   +7 more
semanticscholar   +1 more source