Results 61 to 70 of about 698,346 (390)

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Behaviour influences cholesterol plasma levels in a pig model

Animal, 2007
Little is known about the relationship between feed intake behaviour and cholesterol levels in humans. This can be attributed to the fact that feed intake behaviour in humans is difficult to assess.
W.M. Rauw, O. Portolés, D. Corella, J. Soler, J. Reixach, J. Tibau, J.M. Prat, I. Diaz, L. Gómez-Raya   +8 more
doaj   +1 more source

Molecular characterization of fibroblast growth factor-16 and its role in promoting the differentiation of intramuscular preadipocytes in goat

Animal, 2020
Fat metabolism is an important and complex biochemical reaction in vivo and is regulated by many factors. Recently, the findings on high expression of fibroblast growth factor-16 (FGF16) in brown adipose tissue have led to an interest in exploring its ...
K. Huang, J.J. Liang, Y.Q. Lin, J.J. Zhu, J.Q. Ma, Y. Wang   +5 more
doaj   +1 more source

Association between endometriosis and metabolic syndrome: a cross-sectional study based on the National Health and Nutrition Examination Survey data

Gynecological Endocrinology, 2023
Background Endometriosis has been reported to be associated with metabolism-related diseases, such as hypercholesterolemia and diabetes, while no studies have reported the association between endometriosis and metabolic syndrome.Objective This study aims
Baijia Li, Yuxue Zhang, Liuhang Zhang, Lingyan Zhang   +3 more
doaj   +1 more source

An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. [PDF]

, 2019
Chronic or excess glucocorticoid exposure causes lipid disorders such as hypertriglyceridemia and hepatic steatosis. Angptl4 (angiopoietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, is required for ...
Cheang, Rachel T, Chen, Tzu-Chieh, Fitch, Mark D, Gray, Nora E, Hellerstein, Marc K, Kanamaluru, Deepthi, Lee, Justin Y, Lee, Rebecca A, Tan, Jenna H, Tsai, Sam L, Wang, Jen-Chywan, Yiv, Nicholas   +11 more
core  

The relation between visceral adipose tissue accumulation and biochemical tests in university students. [PDF]

, 2005
We evaluated the visceral adipose tissue accumulation in university students in Okayama prefecture, Japan. Fifty-eight Japanese university students (10 men and 48 women, age 18.4 +/- 0.6 years)were enrolled in this study.
Fujii, Masafumi, Kira, Shohei, Kogashiwa, Michiko, Miyatake, Nobuyuki, Wang, Da-Hong, Yamasato, Teruhiro   +5 more
core   +1 more source

Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials.

Circulation, 2019
Background: Randomized trials of therapies that primarily lowered triglycerides have not consistently shown reductions in cardiovascular events. Methods: We performed a systematic review and trial-level meta-regression analysis of 3 classes of lipid ...
N. Marston, R. Giugliano, K. Im, Michael G. Silverman, M. O’Donoghue, S. Wiviott, B. Ference, M. Sabatine   +7 more
semanticscholar   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Lipid changes in male Albino rats exposed to graded doses of Lead

Ceylon Journal of Science, 2018
In order to determine the lipid changes in male albino rats exposed to graded doses of lead as lead acetate for periods of 4, 8 and 12 weeks, a total of 60 male albino rats were divided into four groups as, A, B, C and D.
B. S. Okediran, A. S. Adah, F. Sanusi, K. Y. Suleiman   +3 more
doaj   +1 more source

Effects of Non‐Aspirin Nonsteroidal Anti‐Inflammatory Drugs on Acute Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite celecoxib, a cyclooxygenase‐2 inhibitor, promoting functional recovery from intracerebral hemorrhage (ICH) by reducing inflammation‐mediated perihematomal edema in rat models, the evidence of its effects on patient outcomes remains limited.
Shin‐Joe Yeh, Sung‐Chun Tang, Li‐Kai Tsai, Jiann‐Shing Jeng   +3 more
wiley   +1 more source