Results 121 to 130 of about 10,516,949 (236)

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

Association of the triglyceride-glucose index and its related parameters with frailty

Lipids in Health and Disease
Background Frailty is a dynamic geriatric condition. Limited studies have examined the association of the triglyceride-glucose (TyG) index and its related indicators [TyG index, triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose ...
Huangyi Yin, Liuqing Guo, Wei Zhu, Weishan Li, Yubo Zhou, Wenyun Wei, Min Liang   +6 more
doaj   +1 more source

Comparison of triglyceride-glucose index and atherogenic index of plasma in euthyroid Hashimoto’s thyroiditis patients and healthy controls

Aim The relationship between insulin resistance and atherosclerosis in euthyroid Hashimoto’s thyroiditis (HT) remains unclear. This study aimed to compare the atherogenic index of plasma (AIP) and triglyceride–glucose (TyG) index between patients with ...
Mustafa Harı, Semra Özkan
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Association Between Triglyceride-Glucose Index and Lung Function Parameters in the General Population Undergoing Health Examinations [PDF]

Yu Yang,1,2 Shuqi Wang,1,3 Boying Jia,1,3 Shuchun Chen1,3 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, People’
Yang Y, Wang S, Jia B, Chen S
core  

Association between triglyceride glucose index-related indices with gallstone disease among US adults

Background Triglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose-waist circumference (TyG-WC)], represents ...
Chang Fu, Xiaocong Li, Yongxin Wang, Junhong Chen, Yibo Yang, Kai Liu   +5 more
core   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

The Triglyceride-Glucose Index: A Cost-Effective Biomarker for Early Detection of Insulin Resistance in Autosomal Dominant Polycystic Kidney Disease [PDF]

Objective: Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary cause of end-stage renal disease, often associated with metabolic disorders, including insulin resistance and diabetes mellitus (DM).
DEĞER, SERPİL MÜGE, KORUCU, BERFU, HEYBELİ, CİHAN, Serpil Müge DEĞER, DELİGÖZ BİLDACI, YELDA, Cihan HEYBELİ, Doğan Can GAVCAR, Atay, İlker, Caner ÇAVDAR, Berfu KORUCU, OKTAN, MEHMET ASI, Gavcar, Doğan Can, Mehmet Ası OKTAN, ÇAVDAR, CANER, Yelda DELİGÖZ BİLDACI, İlker ATAY   +15 more
core   +1 more source

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

Chronic Diseases and Translational Medicine, EarlyView.
Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou, Xijuan Zhang, Liang Zeng, Liheng Zeng, Xiaoyan Hu, Xuhong Jiang, Yahui Wan, Mingxia Ge, Xiaoyan Huang   +8 more
wiley   +1 more source

Empirical study of family nurses dietotherapy scheme in dietary intervention for overweight or obese patients with type 2 diabetes mellitus

Huli yanjiu, 2023
ObjectiveTo explore the effect of diet therapy program guided by family nurses' diet therapy theory on overweight adult obese patients with type 2 diabetes mellitus.MethodsFrom September 2022 to November 2022，63 overweight or obese patients with type 2 ...
WANG Yan, HAN Shifan, ZHU Ruifang, CAO Yan, FENG Yaoqing, CHENG Junxiang   +5 more
doaj