Results 91 to 100 of about 512,588 (331)
Advanced Science, EarlyView.In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou +10 more
wiley +1 more source
Familial combined hyperlipidemia plasma stimulates protein secretion by HepG2 cells
Journal of Lipid Research, 2002 The aim of this study was to evaluate whether soluble factors in plasma of familial combined hyperlipidemia (FC333366) patients affect hepatic protein secretion. Cultured human hepatocytes, i.e., HepG2 cells, were incubated with fasting plasma (20%, v/v,
Marleen M.J. van Greevenbroek +2 more
doaj +1 more source
The relations of metabolic syndrome to anxiety and depression symptoms in children and adults [PDF]
, 2017 Metabolic syndrome is a cluster of five factors (elevated systolic blood pressure, elevated blood glucose, elevated triglycerides, large waist circumference, and decreased HDL) that are related to a greater chance of heart disease, stroke, and diabetes ...
Michael, Jennifer R
core +1 more source
Maternal caregivers have confluence of altered cortisol, high reward-driven eating, and worse metabolic health. [PDF]
, 2019 Animal models have shown that chronic stress increases cortisol, which contributes to overeating of highly palatable food, increased abdominal fat and lower cortisol reactivity. Few studies in humans have simultaneously examined these trajectories.
Epel, Elissa S +3 more
core +2 more sources
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Advanced Science, EarlyView.Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Health Information and Social Security Entitlements [PDF]
, 2013 This study examines whether new health information, obtained through medical screening, affects entitlements to Social Security benefits. Random assignment of information is derived from a unique feature of the Continuous National Health and Nutrition ...
Perry Singleton
core +1 more source
Maternal micronutrient status and decreased growth of Zambian infants born during and after the maize price increases resulting from the southern African drought of 2001-2002. [PDF]
, 2005 OBJECTIVE: To investigate the effects on maternal micronutrient status and infant growth of the increased maize prices that resulted from the southern African drought of 2001-2002. DESIGN: Longitudinal cohort study.
A Tomkins +9 more
core +2 more sources
Advanced Science, EarlyView.Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge +21 more
wiley +1 more source
Inflammatory Effects of Triglycerides
JACC: Basic to Translational Science, 2023 Jordan M. Kraaijenhof, MD +1 more
doaj +1 more source
Systematic review of biochemical biomarkers for neck and upper-extremity musculoskeletal disorders
Scandinavian Journal of Work, Environment & Health, 2016 OBJECTIVE: This study systematically summarizes biochemical biomarker research in non-traumatic musculoskeletal disorders (MSD). Two research questions guided the review: (i) Are there biochemical markers associated with neck and upper-extremity MSD? and
Judith E Gold +9 more
doaj +1 more source