Results 141 to 150 of about 512,588 (331)

Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis

open access: yesJournal of Lipid Research
The availability of genome-wide transcriptomic and proteomic datasets is ever-increasing and often not used beyond initial publication. Here, we applied module-based coexpression network analysis to a comprehensive catalog of 35 mouse genome-wide liver ...
James A. Votava   +5 more
doaj   +1 more source

HDL meets triglyceride

open access: yesJournal of Lipid Research
The study by Liu et al in this issue of the Journal of Lipid Research leverages data from the UK Biobank to explore the impact of HDL-TG on atherosclerotic cardiovascular disease risk. The investigators observed that elevated serum triglyceride levels were associated with reduced HDL particle diameter and with increased HDL-TG.
Tugce Akcan, Fredric B. Kraemer
openaire   +3 more sources

Perturbations of triglycerides but not of cholesterol metabolism are prevented by anti-tumour necrosis factor treatment in rats bearing an ascites hepatoma (Yoshida AH-130) [PDF]

open access: bronze, 1995
Sandra Dessı̀   +8 more
openalex   +1 more source

A combined extract containing Schisandra chinensis (SCE) reduced hepatic triglyceride accumulation in rats fed a high-sucrose diet [PDF]

open access: green, 2023
Haneul Lee   +10 more
openalex   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

open access: yesAdvanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang   +13 more
wiley   +1 more source

The protection of the unsaturated fatty acids of dried grass and sunflower seed against biohydrogenation by rumen micro-organisms : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]

open access: yes, 1974
Ryegrass which had been dried and treated with HCHO was incubated with the rumen contents of a pasture-grazed cow. The protein in the grass was protected from degradation by the rumen microbes.
Smeaton, Duncan Colquhoun
core  

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He   +17 more
wiley   +1 more source

Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage

open access: yesJournal of Lipid Research
De novo lipogenesis (DNL) has been implicated in the development and progression of liver steatosis. Hepatic DNL is strongly influenced by dietary macronutrient composition with diets high in carbohydrate increasing DNL while diets high in fat decrease ...
Lewin Small   +7 more
doaj   +1 more source

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