Results 141 to 150 of about 699,051 (382)
Treating patients with low high-density lipoprotein cholesterol: choices, issues and opportunities
Current Controlled Trials in Cardiovascular Medicine, 2001 Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein (HDL)-cholesterol.
Watts Gerald F
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Advanced Science, EarlyView.This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang +18 more
wiley +1 more source
Diabetes, 2014 Metformin is the first-line drug for the treatment of type 2 diabetes. Besides its well-characterized antihyperglycemic properties, metformin also lowers plasma VLDL triglyceride (TG).
J. Geerling +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang +15 more
wiley +1 more source
The Rate of Absorption of Synthetic Triglycerides in the Rat [PDF]
, 1940 Harry J. Deuel, Lois F. Hallman
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Advanced Science, EarlyView.The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu +8 more
wiley +1 more source
Effect of effective microorganisms on some biochemical parameters in broiler chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2014 This study was conducted to investigate the potential effect of effective microorganisms (EM) on some biochemical parameters which includes; glucose, cholesterol and triglycerides levels in addition to the levels of Alanine aminotransferase (ALT) and ...
S.K. Abd
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ASYMMETRICALLY SUBSTITUTED MIXED ACID TRIGLYCERIDES: ACYL DERIVATIVES OF
, 1951 Erich Baer, Alan G. Newcombe
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Emerging Nanotechnology Strategies for Obesity Therapy
Advanced Science, EarlyView.Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang +5 more
wiley +1 more source
Central lipid detection and the regulation of feeding behavior
Oléagineux, Corps gras, Lipides, 2013 The modern abundance of energy-rich foods combined with a shift to more sedentary lifestyles has led to a thermodynamic imbalance in which excessive caloric intake and reduced energy expenditure account for the prevalence of obesity.
Cansell Céline, Luquet Serge
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