Results 171 to 180 of about 67,879 (252)

Canadian Endocrinologists′ Perspectives on Treatment With Thyroid Hormone Substitutions in Euthyroid and Hypothyroid Patients: A 2023 THESIS Questionnaire Survey

open access: yesClinical Endocrinology, Volume 103, Issue 5, Page 739-748, November 2025.
ABSTRACT Objective The practice of treating hypothyroid and euthyroid patients with thyroid hormones varies between countries, as observed in the recent surveys of European thyroid experts, THESIS. As part of the THESIS initiative, we investigated Canadian endocrinologists′ perspectives on this topic, focusing on combination therapy with either ...
Anna Liu   +11 more
wiley   +1 more source

Rapid Changes in Cholinergic Signaling, Myelination, and Thyroid Signaling Pathway Gene Expression in Amygdala Subnuclei in Response to Social Status Maintenance and Reorganization

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 9, November 2025.
ABSTRACT Male CD‐1 mice form linear social hierarchies and can rapidly reform them following social reorganization. Through tag‐based sequencing in the medial amygdala (MeA), we identified several genes regulating cholinergic signaling, myelination, and thyroid signaling that rapidly shift expression 70 min after animals change social status.
Tyler M. Milewski   +3 more
wiley   +1 more source

Development of a Human Preclinical Platform for the Identification of Neuroprotective Compounds

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 10, November 2025.
Neuroprotection screening on neurons and OLs in oxidative stress and axonal damage assays. Analysis of neurite outgrowth, apoptosis, ROS, OL differentiation and proteomics. Cuprizone model assessed effects on neurodegeneration, inflammation and pro‐myelination.
Raquel Guerrero González   +8 more
wiley   +1 more source

Recent Advances in Interventions Targeting Remyelination and a Systematic Review of Remyelinating Effects of Approved Disease‐Modifying Treatments for Multiple Sclerosis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 11, November 2025.
ABSTRACT Background Regenerative strategies in progressive multiple sclerosis (MS) pose a significant unmet need. Combining immunomodulatory treatment with remyelinating interventions to target the complex underlying pathogenesis appeals as the next frontier in MS therapeutic developments.
Anna‐Victoria De Keersmaecker   +11 more
wiley   +1 more source

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