Results 51 to 60 of about 6,762 (291)

A Novel Big Data Collection System for Ship Energy Efficiency Monitoring and Analysis Based on BeiDou System

Journal of Advanced Transportation, 2021
The call for green shipping is increasing, and the reduction of greenhouse gas emissions from ships becomes more and more important. Traditional ship energy efficiency monitoring is based on the noon reports, which are susceptible to human error and have
Xiangming Zeng, Mingzhi Chen
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Study of trim optimization based on design of experiments and RANS simulation

, 2019
Trim optimization is a particularly easy and cheap way of improving ship performance, reducing fuel oil consumption and lowering emission. The purpose of trim optimization is to obtain the optimal trim to minimize the ship total resistance at the ...
Chen, Jianwei, Shen, Liang, Yu, Cheng
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Design optimization of multi-objective proportional–integral–derivative controllers for enhanced handling quality of a twin-engine, propeller-driven airplane

Advances in Mechanical Engineering, 2020
Herein, the design optimization of multi-objective controllers for the lateral–directional motion using proportional–integral–derivative controllers for a twin-engine, propeller-driven airplane is presented.
Mohsen Rostami, Joon Chung, Hyeong Uk Park   +2 more
doaj   +1 more source

A Simple Method of Ship Dynamic Trimming Optimization [PDF]

Proceedings of the 4th International Conference on Mechatronics, Materials, Chemistry and Computer Engineering 2015, 2015
In order to cope"Guidelines for voluntary use of Energy Efficiency Operational Indicators( EEOI)", a simple method of adjusting ship trimming of a voyage has been attempted,which can minimize the energy consumption and economize cost.A method of ship dynamic trimming optimization base on loading computer is introduced by theories analysis and sea trial
Fanyi Kong, Na Jiang, Xiangxin Cheng, Zhaoxin Zhou, Qiang Zhang   +4 more
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Surrogate Model Considering Trim Condition for Design Optimization of High-Aspect-Ratio Flexible Wing

, 2022
An improved, bilevel surrogate model to optimize aerodynamic/nonlinear structural coupled problems, considering trim conditions, is proposed in this paper. The proposed model is applied to a high-aspect-ratio flexible wing.
Kim, Euiyoung, Chang, Seongmin, Im, Sunyoung, Park, Kyunghyun, Lee, Dong-Ho, Cho, Maenghyo   +5 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source