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In Vitro and in Vivo Study of the Antithyroid Side Effects of Trimeprazine
Toxicology and Applied Pharmacology, 1999Trimeprazine (TMP), a phenothiazine used as antipsychotic drug, was previously shown to induce a decrease in thyroid hormone serum levels in rats. Different mechanisms might be involved, mainly (i) a central mechanism, involving a reduction of thyroid-stimulating hormone (TSH) secretion; (ii) a peripheral mechanism, acting upon the synthesis of thyroid
M F, Sauvage +5 more
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Double-Blind Evaluation of Trimeprazine
A.M.A. Archives of Dermatology, 1959Recently, a phenothiazine derivative, trimeprazine (Temaril * ), was reported on 1 in fairly glowing terms as being valuable in the relief of itching when taken orally. For example, Callaway and Olansky 1 found that 82% of their patients with various skin conditions obtained good or excellent relief of itching while taking the drug.
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A TRIAL OF TRIMEPRAZINE IN ITCHING DERMATOSES.
British Journal of Dermatology, 1959T E, ANDERSON, D, CHALMERS
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Trimeprazine as oral premedication in children.
Journal of the Indian Medical Association, 1991The effect of oral trimeprazine alone or in combination with either atropine or glycopyrrolate or pethidine as oral premedication in children was studied. The effects of different drug combinations were evaluated in respect of pre-operative sedation, salivary secretion, induction characteristic, postoperative sedation and postoperative vomiting.
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