Results 81 to 90 of about 588 (125)
Mechanism-based inhibition of squalene epoxidase by phenothiazines for lipid metabolism disruption using repurposed antipsychotic drugs. [PDF]
Sci RepKamel EM +7 more
europepmc +1 more source
Intelligent Recommendation Systems Powered by Consensus Neural Networks: The Ultimate Solution for Finding Suitable Chiral Chromatographic Systems? [PDF]
Anal ChemSagrado S +4 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Agranulocytosis Induced by Trimeprazine
New England Journal of Medicine, 1959PHENOTHIAZINE derivatives have long been known to have serious toxic effects in a small number of susceptible persons.
Philip S Brachman
exaly +3 more sources
Pharmacokinetics of Trimeprazine in Children
Pharmacology & Toxicology, 1990The pharmacokinetics of trimeprazine (alimemazine) were studied over 24 hr in six children after a recommended preanaesthetic oral dose of 3 mg · kg‐1. The degree of sedation before anaesthesia was evaluated. Median maximal venous blood drug concentration was 0.357 μmol · 1‐1, 1–2 hr after oral ingestion, half‐life 6.8 hr and AUC0‐∞h 2.758 μmol · 1‐1 ...
S, Sponheim +3 more
openaire +2 more sources
Archives of Dermatology, 1960
Introduction In 1958 a new phenothiazine derivative, trimeprazine, * was introduced as a nonspecific oral agent for the treatment of pruritus. Preliminary studies indicated its usefulness in a wide variety of itching dermatoses which are, according to our present knowledge, unrelated etiologically. The mechanism of action is obscure.
W E, CLENDENNING +2 more
openaire +2 more sources
Introduction In 1958 a new phenothiazine derivative, trimeprazine, * was introduced as a nonspecific oral agent for the treatment of pruritus. Preliminary studies indicated its usefulness in a wide variety of itching dermatoses which are, according to our present knowledge, unrelated etiologically. The mechanism of action is obscure.
W E, CLENDENNING +2 more
openaire +2 more sources
Premedication for children with oral trimeprazine and droperidol [PDF]
Anaesthesia, 1984 Summary In 60 children aged 1–9 years, weighing under 33 kg, oral trimeprazine and oral trimeprazine plus droperidol were compared as premedicants in a controlled, double‐blind clinical trial. The addition of droperidol to the trimeprazine syrup produces greater uniformity in pre‐operative sedation, a low incidence of postoperative ...
D J, Layfield, A K, Walker
exaly +3 more sources
TRIMEPRAZINE TARTRATE FOR PREMEDICATION OF CHILDREN
Lancet, The, 1959R W, COPE, W J, GLOVER
exaly +3 more sources
COMPARATIVE TRIAL OF TRIMEPRAZINE AND AMYLOBARBITONE IN PRURITUS
Lancet, The, 1963P Armitage
exaly +2 more sources