Results 81 to 90 of about 545 (124)
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Agranulocytosis Induced by Trimeprazine
New England Journal of Medicine, 1959PHENOTHIAZINE derivatives have long been known to have serious toxic effects in a small number of susceptible persons.
Philip S Brachman, Brachman Philip S
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TRIMEPRAZINE TARTRATE FOR PREMEDICATION OF CHILDREN
Lancet, The, 1959R W, COPE, W J, GLOVER
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A COMPARATIVE TRIAL OF TRIMEPRAZINE AND AMYLOBARBITONE IN PRURITUS
Lancet, The, 1963F F Hellier
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Archives of Dermatology, 1960
Introduction In 1958 a new phenothiazine derivative, trimeprazine, * was introduced as a nonspecific oral agent for the treatment of pruritus. Preliminary studies indicated its usefulness in a wide variety of itching dermatoses which are, according to our present knowledge, unrelated etiologically. The mechanism of action is obscure.
W E, CLENDENNING +2 more
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Introduction In 1958 a new phenothiazine derivative, trimeprazine, * was introduced as a nonspecific oral agent for the treatment of pruritus. Preliminary studies indicated its usefulness in a wide variety of itching dermatoses which are, according to our present knowledge, unrelated etiologically. The mechanism of action is obscure.
W E, CLENDENNING +2 more
openaire +2 more sources
Pharmacokinetics of Trimeprazine in Children
Pharmacology & Toxicology, 1990The pharmacokinetics of trimeprazine (alimemazine) were studied over 24 hr in six children after a recommended preanaesthetic oral dose of 3 mg · kg‐1. The degree of sedation before anaesthesia was evaluated. Median maximal venous blood drug concentration was 0.357 μmol · 1‐1, 1–2 hr after oral ingestion, half‐life 6.8 hr and AUC0‐∞h 2.758 μmol · 1‐1 ...
S, Sponheim +3 more
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COMPARATIVE TRIAL OF TRIMEPRAZINE AND AMYLOBARBITONE IN PRURITUS
Lancet, The, 1963P Armitage
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Double-Blind Evaluation of Trimeprazine
A.M.A. Archives of Dermatology, 1959Recently, a phenothiazine derivative, trimeprazine (Temaril * ), was reported on 1 in fairly glowing terms as being valuable in the relief of itching when taken orally. For example, Callaway and Olansky 1 found that 82% of their patients with various skin conditions obtained good or excellent relief of itching while taking the drug.
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