Results 101 to 110 of about 738 (155)
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Prolonged Neuromuscular Blockade Associated with Trimethaphan
Anesthesia and Analgesia, 1976A case of prolonged neuromuscular blockade associated with the administration of trimethaphan to a neurosurgical patient aged 29 is believed to be the possible result of interaction between trimethaphan, a ganglionic-blocking drug, and muscle relaxant. This possibility should be kept in mind when the administration of trimethaphan is being considered.
S L, Wilson +3 more
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Blockade of Smoking Satisfaction Using the Peripheral Nicotinic Antagonist Trimethaphan
Pharmacology Biochemistry and Behavior, 1999The present study was conducted to investigate the role of peripheral nicotinic receptors in mediating the rewarding effects of cigarette smoking. Twelve cigarette smokers rated cigarettes after intravenous infusion of the short-acting peripheral nicotinic receptor antagonist trimethaphan and after placebo (saline) infusions.
J E, Rose +4 more
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Effect of Trimethaphan on Intraocular Pressure in Electroconvulsive Therapy
JAMA - Journal of the American Medical Association, 1963According to Hibbeler, 4 patients suffering from glaucoma rather frequently have mental disturbances, and when electroconvulsive therapy becomes necessary the problem arises of how such treatment will affect the glaucoma. A report of ten patients suffering from glaucoma treated with electroconvulsive therapy at different clinics in the United States ...
J O, OTTOSSON, I, RENDAHL
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Mixtures of Sodium Nitroprusside and Trimethaphan for Induction of Hypotension
Anesthesia and Analgesia, 1991A mixture of sodium nitroprusside (SNP) and trimethaphan, empirical 1:10 weight ratio, has been advocated to decrease untoward side effects of SNP when used to induce hypotension during anesthesia and operation. The purpose of this study was to investigate the effects of various ratios of mixtures of SNP and trimethaphan on heart rate (HR), renal ...
K, Nakazawa +4 more
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Trimethaphan as a glutamate inhibitor at the Crayfish neuromuscular junction
Brain Research, 1983At the crayfish neuromuscular junction trimethaphan reduced the amplitude of both the glutamate-induced synaptic current and the excitatory junctional current in a dose-dependent manner at concentrations greater than 5 microM. These effects were dependent on membrane potential.
H, Shinozaki, M, Ishida
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Respiratory Paralysis During Treatment of Hypertension With Trimethaphan Camsylate
Archives of Internal Medicine, 1976Four cases are reported in which respiratory arrest occurred coincident with the intravenous administration of large doses of trimethaphan camsylate (Arfonad) to control hypertension. The mechanism of the respiratory depression is unknown, but it may have been related to a direct effect of trimethaphan on the respiratory center or to a curare-like ...
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Prolonged Apnea Following Trimethaphan and Succinylcholine
Anesthesiology, 1979Oksana Lockridge
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Trimethaphan Camsylate in Hemorrhagic Shock
Archives of Surgery, 1964The ill effects of excessive sympathetic stimulation in animals subjected to prolonged oligemic hypotension have been documented by many observers.1-6These observations have led to the experimental and clinical use of ganglionic or adrenergic blocking agents to prevent harmful vasoconstriction in shock.
R W, HOPKINS, F A, SIMEONE
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Cerebral tissue lactate in trimethaphan-induced hypotension
The American Journal of Surgery, 1971Abstract Ischemic effects of profound sustained hypotension upon the brain utilizing trimethaphan have been investigated because of frequent clinical utilization by surgeons. In ten dogs hypotension (30 to 40 mm Hg MAP) was sustained for one hour. Cerebral tissue lactate accumulation was assessed at five, thirty, and sixty minutes.
G E, Locke, D, Yashon, W E, Hunt
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