Results 111 to 120 of about 550 (146)

Cerebral tissue lactate in trimethaphan-induced hypotension

The American Journal of Surgery, 1971
Abstract Ischemic effects of profound sustained hypotension upon the brain utilizing trimethaphan have been investigated because of frequent clinical utilization by surgeons. In ten dogs hypotension (30 to 40 mm Hg MAP) was sustained for one hour. Cerebral tissue lactate accumulation was assessed at five, thirty, and sixty minutes.
G E, Locke, D, Yashon, W E, Hunt
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Trimethaphan Camsylate

2000
Abstract The sulfonium derivative trimethaphan is used as a vasodepressor agent during surgical procedures and in hyper tensive emergencies. Trimethaphan acts as a ganglionic blocking agent by competing with acetylcholine for the postsynaptic cholinergic receptor; this is in contrast to other ganglionic-blocking agents (e.g ...
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Preservation of Platelet Function During Trimethaphan Infusion

Anesthesiology, 1990
The effect of trimethaphan (Arfonad) infusion on platelet function was prospectively evaluated in 38 (n = 38) patients (28 patients receiving trimethaphan, ten control patients) undergoing elective cardiac surgery. Any patient with a positive history for the ingestion of medication known to interfere with platelet function was excluded from the study ...
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Effects of Trimethaphan and Sodium Nitroprusside on Hydrolysis of Succinylcholine  in Vitro

Anesthesiology, 1977
The use of hypotensive agents in combination with succinylcholine may be necessary. Since trimethaphan has been reported to prolong the action of succinylcholine, the authors studied the abilities of trimethaphan and sodium nitroprusside to inhibit hydrolysis of succinylcholine by pseudocholinesterase in vitro.
G S, Sklar, K W, Lanks
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TRIMETHAPHAN

Anesthesiology, 1986
R. Hines, P. G. Barash
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In Defense of Trimethaphan for Use in Preeclampsia

Obstetric Anesthesia Digest, 1986
M, Sosis, B, Leighton
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The Prognostic Value of the Trimethaphan Test

Southern Medical Journal, 1967
J F, Patterson, J W, Pearson, J S, Redding   +2 more
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TRIMETHAPHAN IS NOT INACTIVATED BY PSEUDOCHOLINESERASE

Anesthesiology, 1989
T. A. Alston, F. M. deBros
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Aminoglycoside antibiotics: interaction with trimethaphan at the neuromuscular junctions.

Drugs under experimental and clinical research, 1987
Trimethaphan, a ganglionic blocking agent which is administered by intravenous drip to produce controlled hypotension during surgery, produces a complete neuromuscular blockade at the isolated phrenic nerve-hemidiaphragm preparation of the rat at a concentration of 0.3 mmol X l-1. This blockade is not reversed by neostigmine, a cholinesterase inhibitor,
A G, Paradelis, L G, Crassaris, D N, Karachalios, C J, Triantaphyllidis   +3 more
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Trimethaphan or Nitroprusside in the Setting of Intracranial Hypertension

Clinical Neuropharmacology, 1988
J M, Murphy, J I, Sage
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