Results 131 to 140 of about 915 (177)

Trimethaphan as a glutamate inhibitor at the Crayfish neuromuscular junction

Brain Research, 1983
At the crayfish neuromuscular junction trimethaphan reduced the amplitude of both the glutamate-induced synaptic current and the excitatory junctional current in a dose-dependent manner at concentrations greater than 5 microM. These effects were dependent on membrane potential.
H, Shinozaki, M, Ishida
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[Neuromuscular blocking action of trimethaphan camsylate and cholinesterase].

Masui. The Japanese journal of anesthesiology, 1985
Y Tsukawaki, Mizuo Miyazaki
openalex   +2 more sources

Trimethaphan camsylate (Arfonad) and human plasma cholinesterase.

Research communications in chemical pathology and pharmacology, 1979
These results for the first time document that the brief duration of action of the ganglionic blocker, Arfonad (trimethaphan camsylate), is not due to inactivation by plasma cholinesterase. Inhibition of the enzyme in vitro by Arfonad was not altered by prior incubation of the drug in plasma at 37 degrees C for up to 16 hours nor by treatment with ...
A H, Anton, S, Czinn, J, Jazwa, L, Tam, L, Amaranath   +4 more
openaire   +1 more source

TRIMETHAPHAN

Anesthesiology, 1986
R. Hines, P. G. Barash
openaire   +1 more source

Ultra-high Dose Trimethaphan in an Infant with Severe Hypertension

Journal of Toxicology: Clinical Toxicology, 1996
Trimethaphan camsylate is a potent antihypertensive drug used to induce systemic arterial hypotension in patients undergoing major surgery and to treat severe systemic hypertension. The pharmacokinetics and pharmacodynamics of trimethaphan administered in the usual clinical dosages have been previously reported.
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Cerebral function during trimethaphan‐induced hypotension

Neurology, 1973
A, Magness, D, Yashon, G, Locke, W, Wiederholt, W E, Hunt   +4 more
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The Prognostic Value of the Trimethaphan Test

Southern Medical Journal, 1967
J F, Patterson, J W, Pearson, J S, Redding   +2 more
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Trimethaphan

2011
Tor Sandven, Stephen Robinson
openaire   +1 more source

TRIMETHAPHAN IS NOT INACTIVATED BY PSEUDOCHOLINESERASE

Anesthesiology, 1989
T. A. Alston, F. M. deBros
openaire   +1 more source

Aminoglycoside antibiotics: interaction with trimethaphan at the neuromuscular junctions.

Drugs under experimental and clinical research, 1987
Trimethaphan, a ganglionic blocking agent which is administered by intravenous drip to produce controlled hypotension during surgery, produces a complete neuromuscular blockade at the isolated phrenic nerve-hemidiaphragm preparation of the rat at a concentration of 0.3 mmol X l-1. This blockade is not reversed by neostigmine, a cholinesterase inhibitor,
A G, Paradelis, L G, Crassaris, D N, Karachalios, C J, Triantaphyllidis   +3 more
openaire   +1 more source