Results 11 to 20 of about 34,128 (187)

Correction: Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Tripanosoma cruzi Infection [PDF]

open access: yesPLOS ONE, 2017
[This corrects the article DOI: 10.1371/journal.pone.0153038.].
Camila França Campos   +8 more
openaire   +4 more sources

Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide

open access: yesMolecules, 2000
Goyazensolide, a biologically active natural product classified as a furoheliangolide, was transformed in a phthalimide derivative that showed an enhanced biological activity against Tripanosoma cruzi.
Mauricio Gomes Constantino   +2 more
doaj   +2 more sources

Casos Autóctonos de Trypanosomiasis Americana (Enfermedad de Chagas) Descubiertos en el Departamento de Piura

open access: yesActa Médica Peruana, 1982
Conviene señalar brevemente que en 1909, Carlos Chagas, epidemiólogo brasileño, descubre en el Estado de Minas Gerais (Brasil) una enfermedad infecciosa producida por un protozoario flagelado de Chagas, en homenaje de su maestro Oswaldo Cruzi, denominó “
Cronwell Vassallo F.
doaj   +1 more source

Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy [PDF]

open access: yesFrontiers in Immunology, 2018
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi and affects over 8 million people worldwide. In spite of a powerful innate and adaptive immune response in acute infection, the parasite evades eradication, leading to a chronic ...
Christophe Chevillard   +21 more
doaj   +2 more sources

Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction–Optimization Strategy Applied to Paullones

open access: yesChemMedChem, Volume 18, Issue 10, May 16, 2023., 2023
Treatment of Chagas disease, African sleeping sickness and Leishmaniasis is currently limited to few, unfavorable drugs. We discovered novel antitrypanosomal compounds via molecular simplification of an original molecule (MOL2008) displaying limited selectivity.
Jens C. Lindhof   +9 more
wiley   +1 more source

A Trypanosoma cruzi strain from southern Mexico is more virulent for male mice in part by blocking the immune response

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: Chagas disease is a neglected disease in the American continent. The southern Mexican state of Chiapas has the highest incidence rate of Chagas disease in the country.
Celeste Amaranta Palma-González   +8 more
doaj   +1 more source

Contribuição para o estudo dos mecanismos de transmissão do agente etiológico da doença de Chagas A contribution to the study of the mechanisms of transmission of the etiological agent of "Chagas" disease

open access: yesRevista de Saúde Pública, 1987
Foram capturados no Município de Ribeirão Preto, SP, Brasil, exemplares de gambá, Didelphis albiventris. Na medida em que os exemplares chegavam ao laboratório foram submetidos a exames de sangue a fresco, hemoculturas e xenodiagnósticos, com o propósito
Rosa Domingues Ribeiro   +2 more
doaj   +1 more source

Inmunización a Tripanosoma cruzi con antígenos tratados con detergentes

open access: yesRevista Ecuatoriana de Medicina y Ciencias Biológicas, 2017
C 3H/ Anf mice were immunized with Lubrol or cholate- treated culture forms of the Tuluhuén strain of Trypanosoma cruzi and subsequently challenged with the homologous bloodstream forms. The equivalent of 1x108 – 2x108 detergent-treated culture forms were injected intraperitoneally, intramuscularly or subcutaneously.
Carlos Soria, Donald Dusanic
openaire   +2 more sources

Infecção experimental de Calomys callosus (Rodentia Cricetidae) com Trypanosoma cruzi Results of the experimental infection of Calomys callosus (Rodentia) with human strains of Trypanosoma cruzi

open access: yesRevista de Saúde Pública, 1982
São apresentados resultados sobre a infecção experimental de Calomys callosus (Rodentia) e duas cepas (Y e Berenice) de Trypanosoma cruzi, isoladas de casos humanos.
Monamaris M. Borges   +2 more
doaj   +1 more source

The avirulence of the cultivated Y strain of Trypanosoma cruzi: IV. The effect of immunosuppressive agents in mice

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1971
Drogas imunossupressoras (Azathioprina e Methotrexato) que se mostraram capazes de agravar infecções experimentais por Trypanosoma cruzi virulento (cepa Y), em camundongos, não conseguiram favorecer o aparecimento de qualquer sinal de infecção em animais
Humberto Menezes
doaj   +1 more source

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