Results 91 to 100 of about 2,448 (132)

GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice. [PDF]

JCI Insight
Takahashi K, Rensing NR, Eultgen EM, Williams LL, Wang SH, Nelvagal HR, Le SQ, Roberts MS, Doray B, Han EB, Dickson PI, Wong M, Sands MS, Cooper JD.   +13 more
europepmc   +1 more source

Enzyme Replacement Therapy for CLN2 Disease: MRI Volumetry Shows Significantly Slower Volume Loss Compared with a Natural History Cohort. [PDF]

AJNR Am J Neuroradiol
Gaur P, Gissen P, Biswas A, Mankad K, Sudhakar S, D'Arco F, Schulz A, Fiehler J, Sedlacik J, Löbel U.   +9 more
europepmc   +1 more source

Embracing the future: Neonatal screening for epileptic syndromes. [PDF]

Epilepsia
Nabbout R, Kuchenbuch M.
europepmc   +1 more source

Plant Antimicrobial Oligopeptides with Anticancer Properties as a Source of Biologically Active Peptides-An <i>In Silico</i> Study. [PDF]

Int J Mol Sci
Jakubczyk A, Rybczyńska-Tkaczyk K, Grenda A.   +2 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Recombinant human tripeptidyl peptidase-1 infusion to the monkey CNS: Safety, pharmacokinetics, and distribution

Toxicology and Applied Pharmacology, 2014
CLN2 disease is caused by deficiency in tripeptidyl peptidase-1 (TPP1), leading to neurodegeneration and death. The safety, pharmacokinetics (PK), and CNS distribution of recombinant human TPP1 (rhTPP1) were characterized following a single intracerebroventricular (ICV) or intrathecal-lumbar (IT-L) infusion to cynomolgus monkeys. Animals received 0, 5,
Mark T Butt, Donald G Musson, Charles A O'Neill   +2 more
exaly   +4 more sources

The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts

Biological Chemistry, 2019
Abstract Incidental detection of pancreatic cysts has increased dramatically over the last decade, but risk stratification and clinical management remain a challenge. Mucinous cysts are precursor lesions to pancreatic cancer, however, the majority are indolent.
Sam L, Ivry, Giselle M, Knudsen, Francesco, Caiazza, Jeremy M, Sharib, Katrin, Jaradeh, Matthew, Ravalin, Anthony J, O'Donoghue, Kimberly S, Kirkwood, Charles S, Craik   +8 more
openaire   +2 more sources