Results 31 to 40 of about 51,803 (231)

Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins

open access: yesComputational and Structural Biotechnology Journal, 2021
In plants, AAA-adenosine triphosphatase (ATPase) Cell Division Control Protein 48 (CDC48) uses the force generated through ATP hydrolysis to pull, extract, and unfold ubiquitylated or sumoylated proteins from the membrane, chromatin, or protein complexes.
Junrui Zhang   +3 more
doaj   +1 more source

Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]

open access: yes, 2017
In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela   +4 more
core   +1 more source

Type I Collagen Receptor (α2β1) Signaling Promotes Prostate Cancer Invasion through RhoC GTPase

open access: yesNeoplasia: An International Journal for Oncology Research, 2008
The most frequent site of metastasis in human prostate cancer (PCa) is the bone. Preferential adhesion of PCa cells to bone-specific factors may facilitate the selective metastasis of the skeleton.
Christopher L. Hall   +5 more
doaj   +1 more source

Adenosine triphosphatase staining of dermatophytes

open access: yesActa Dermato-Venereologica, 1971
No abstract ...
W B, Shelley, L, Juhlin
openaire   +2 more sources

Late-onset thymidine kinase 2 deficiency: a review of 18 cases [PDF]

open access: yes, 2019
BACKGROUND: TK2 gene encodes for mitochondrial thymidine kinase, which phosphorylates the pyrimidine nucleosides thymidine and deoxycytidine. Recessive mutations in the TK2 gene are responsible for the 'myopathic form' of the mitochondrial depletion ...
Caballero Eraso, Candelaria   +9 more
core   +1 more source

Plasmodium RNA triphosphatase validation as antimalarial target

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance
Target-based approaches have traditionally been used in the search for new anti-infective molecules. Target selection process, a critical step in Drug Discovery, identifies targets that are essential to establish or maintain the infection, tractable to ...
Sonia Moliner-Cubel   +11 more
doaj   +1 more source

Mechanism of NaCl transport-stimulated prostaglandin formation in MDCK cells [PDF]

open access: yes, 1987
Recently we have found that stimulation of NaCl transport in high-resistance MDCK cells enhances their prostaglandin formation. In the present study, we investigated the mechanisms by which prostaglandin formation could be linked to the ion transport in ...
Bauer, C.   +4 more
core   +1 more source

Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome ActivationSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2020
Background & Aims: Ral guanosine triphosphatase–activating protein α2 (RalGAPα2) is the major catalytic subunit of the negative regulators of the small guanosine triphosphatase Ral, a member of the Ras subfamily.
Tomoya Iida   +12 more
doaj   +1 more source

Endogenous Mammalian Cardiotonic Steroids—A New Cardiovascular Risk Factor?—A Mini-Review

open access: yesLife, 2021
The role of endogenous mammalian cardiotonic steroids (CTS) in the physiology and pathophysiology of the cardiovascular system and the kidneys has interested researchers for more than 20 years. Cardiotonic steroids extracted from toads or plants, such as
Natalia Słabiak-Błaż, Grzegorz Piecha
doaj   +1 more source

Effect in vitro of the Phenobarbital on the Activity of the Enzyme Adenosine Triphosphatase (ATPase) of Sodium and Potassium Dependent in Human Placenta.

open access: yesMedisur, 2007
Background: Most of the drugs can pass to the fetus through the placenta, conditioning alterations of the development and fetal growth. Objective: To evaluate the effect in vitro of Phenobarbital on the activity of adenosine triphosphatase of sodium and ...
María De Jesús Sánchez Bouza   +1 more
doaj   +2 more sources

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