Results 201 to 210 of about 406,491 (336)

A comparative analysis of mutational profiles between triple-negative breast cancer and non-triple-negative breast cancer. [PDF]

Discov Oncol
Li W, Feng C, Zhou S.
europepmc   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

CANT1 as a novel prognostic biomarker in triple-negative breast cancer. [PDF]

Oncol Lett
Bayram D, Çolak A, Karabulut Ş, Özsan Çelebi SN, Hafizoğlu E, Türkay DÖ, Bal Ö, Algin E, Yücel Ş, Şendur MAN, Civelek B, Uçar G.   +11 more
europepmc   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Targeting the RXR Pathway for the Prevention of Triple-Negative Breast Cancer. [PDF]

Cancer Prev Res (Phila)
Moyer CL, Hill JL, Coleman D, Lanier A, Ma Y, Liu X, Kawedia J, Contreras A, Vuligonda V, Savage MI, Sanders ME, Mohammed A, Sei S, Brown PH, Mazumdar A.   +14 more
europepmc   +1 more source

Triple-negative breast cancer in the elderly

The Breast Journal, 2017
Elena, Shagisultanova, Jose, Mayordomo, Anthony D, Elias   +2 more
openaire   +2 more sources

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

Advanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen, Xiao‐Dan Ma, Shui‐Dan Xu, Ao‐Tian Mo, Min‐Hua Deng, Jun‐Han Wu, Wei‐Tao Zhuang, Jin‐Ling Duan, Shu‐Huan Xie, Jin‐Long Lin, Peng Lin, Ji‐Ming Tang, Hai‐Yu Zhou, Xiao‐Song Ben, Gui‐Bin Qiao, Dan Xie   +15 more
wiley   +1 more source

Proteogenomic decoding of chemotherapy resistance in patients with triple-negative breast cancer. [PDF]

Genome Biol
Lee DK, Kim MH, Hwang Y, Kim SG, Ryu WJ, Kim GU, Yun HM, Park S, Lee JD, Han HJ, Kim GM, Kim KH, Park JB, Kim MJ, Koo JS, Kim JY, Park HS, Kim SI, Gee HY, Park S, Sohn J.   +20 more
europepmc   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

DUSP1: Triple-Negative Breast Cancer and Therapeutic Potential. [PDF]

Curr Oncol
Niture S, Thotala D, Jaboin J, Seneviratne D.   +3 more
europepmc   +1 more source