Results 271 to 280 of about 171,342 (310)

Apoptosis-driven synergistic anti-cancer efficacy of ethyl acetate extract of Memecylon sisparense Gamble leaves and doxorubicin in in-vitro and in-vivo models of triple-negative breast cancer.

Pathology, Research and Practice, 2023
In the spectrum of breast neoplasms, approximately 15 to 20% of all diagnosed cases are triple-negative breast carcinoma. TNBC grows and spreads faster than other invasive breast cancers and has a worse prognosis.
J. Uppu, V. Challa, N. Syamprasad, Pavanprasanth Manepalli, Vgm Naidu, Asha Syed, S. Roshan, B. Tazneem, W. Almalki, Khalid Saad Alharbi, Gaurav Gupta   +10 more
semanticscholar   +1 more source

Pathology of Triple Negative Breast Cancer.

Seminars in Cancer Biology, 2020
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone receptors expression and HER2 gene amplification and represents 24% of newly diagnosed breast neoplasms.
F. Borri, Annarita Granaglia
semanticscholar   +1 more source

Low-grade triple-negative breast carcinomas. A report of 2 cases and an update of current concepts.

Revista Española de Patología, 2021
Triple negative breast cancer is defined by the lack of expression of estrogen, progesterone and HER2 receptors. Significant molecular, morphological and clinical heterogeneity is present in this group of neoplasms.
J. Ruiz, M. Recuero, J. D. Cárdenas, I. Cifuentes, Justo Alvarez, C. Romero, J. Chacón   +6 more
semanticscholar   +1 more source

CD151 Promotes Cancer Progression in Triple-Negative Breast Cancer by Inducing EMT through the MAPK Signaling Pathway

Breast Cancer
Background Breast cancer has become one of the most prevalent malignant neoplasms among women, poses a significant threat to public health. As a member of the tetraspanin family of proteins, CD151 is implicated in tumor progression and has been shown to ...
Haishu Lv, Beibei Zhang, Xi Weng, Youjia Li, Chao Deng, Rui Wang, Lei Shi, Yuanqin Yin   +7 more
semanticscholar   +1 more source

Development and validation of an artificial intelligence system for triple-negative breast cancer identification and prognosis prediction: a multicentre retrospective study

EClinicalMedicine
Summary Background Triple-negative breast cancer (TNBC), recognised as the most aggressive subtype of breast cancer, has a high recurrence rate and poor treatment outcomes.
Xiu-Ming Zhang, Hua-Jun Zhou, Qing Chen, Xi Wang, Yu Fu, Cheng Jin, Fengtao Zhou, Jing-ping Wang, Qiuyu Cai, Ji-Li Wang, Bo Luo, M. Hu, C. Yao, Xia Yang, Ya-li Xu, Jing Zhang, Hao Chen   +16 more
semanticscholar   +1 more source

Cutaneous nodules as a first presentation in triple-negative breast cancer

, 2021
Out of all skin neoplasms, metastasis accounts for only about 2%, and breast cancer is the second commonest malignancy to metastasize to the skin after malignant melanoma. Although triple-negative breast cancer patients tend to have metastatic disease at
S. Olarinoye-Akorede, Desiree Jimeta, Gboyega M. Olarinoye, S. Adewuyi   +3 more
semanticscholar   +1 more source

Metastatic triple‐negative breast carcinoma mimicking melanoma: A potential diagnostic pitfall

Journal of cutaneous pathology
Melanoma, with its diverse histopathologic characteristics, can mimic both benign nevi and neoplasms of various cell lineages. Immunohistochemistry (IHC) can play a vital role in melanoma diagnosis, particularly when the cell lineage is unclear on ...
Rebecca Fliorent, C. Benedetto, Zachary Theroux   +2 more
semanticscholar   +1 more source

Association between obesity and triple-negative breast cancer: a systematic qualitative review

Mastology
Introduction: The relation between obesity and triple-negative breast cancer (TNBC) is not totally elucidated. TNBC represents a heterogeneous group of aggressive growth neoplasms.
L. Iervolino, S. Moraes, J. Filassi, E. Baracat, Sérgio Masili-Oku   +4 more
semanticscholar   +1 more source

Triple negative breast cancer: microRNA expression profile and novel discriminators according to BRCA1 status

Journal of Cellular Physiology, 2019
Triple‐negative breast cancer (TNBC) represents 15% of breast carcinomas. More than 80% of women with a breast cancer associated with a breast cancer type 1 (BRCA1) mutation develop a TNBC.
F. Abdel-Sater, M. Najar, H. Fayyad-kazan   +2 more
semanticscholar   +1 more source