Results 231 to 240 of about 1,687 (297)

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

Single-quantum sodium MRI at 3 T for separation of mono- and bi-T₂ sodium signals. [PDF]

Sci Rep
Qian Y, Lin YC, Chen X, Ge Y, Lui YW, Boada FE.   +5 more
europepmc   +1 more source

Functional screen for subtype specificity of voltage sensor–targeted Kv7 potentiators

British Journal of Pharmacology, EarlyView.
Background and Purpose Voltage‐gated Kv7 (potassium channel subfamily Q [KCNQ]) potassium channels are powerful modulators of neuronal excitability. ICA‐069673 is a N‐aryl benzamide drug that targets the voltage‐sensing domain (VSD) of Kv7.2 with strong selectivity over Kv7.3 or Kv7.5, but the molecular basis of this selectivity remains poorly ...
Richard Kanyo, Thomas M. Hammond, Alice W. Wang, Caroline K. Wang, Varun Aggarwal, Shawn M. Lamothe, Harley T. Kurata   +6 more
wiley   +1 more source

The Accuracy of Predictive Analytics in Forecasting Emergency Department Volume Before and After Onset of COVID-19. [PDF]

West J Emerg Med
Napoli AM, Smith-Shain R, Lin T, Baird J.   +3 more
europepmc   +1 more source

Story2Board: A Training‐Free Approach for Expressive Visual Storytelling

Computer Graphics Forum, EarlyView.
Abstract We present Story2Board, a training‐free framework for expressive storyboard generation from natural language. Existing methods narrowly focus on subject identity, overlooking key aspects of visual storytelling such as spatial composition, background evolution, and narrative pacing.
D. Dinkevich, M. Levy, O. Avrahami, D. Samuel, D. Lischinski   +4 more
wiley   +1 more source

Surgery and positive Bakry-Émery Ricci curvature. [PDF]

Calc Var Partial Differ Equ
Reiser P, Tripaldi F.
europepmc   +1 more source

OUGS: Active View Selection via Object‐aware Uncertainty Estimation in 3DGS

Computer Graphics Forum, EarlyView.
Abstract Recent advances in 3D Gaussian Splatting (3DGS) have achieved state‐of‐the‐art results for novel view synthesis. However, efficiently capturing high‐fidelity reconstructions of specific objects within complex scenes remains a significant challenge.
Haiyi Li, Qi Chen, Denis Kalkofen, Hsiang‐Ting Chen   +3 more
wiley   +1 more source

A feature-enhanced knowledge graph neural network for machine learning method recommendation. [PDF]

PeerJ Comput Sci
Zhang X, Guo J.
europepmc   +1 more source

Skeletal‐Driven Animation of Anatomical Humans via Neural Deformation Gradients

Computer Graphics Forum, EarlyView.
Abstract Most real‐time animation techniques for digital humans are limited to deforming the outer skin surface. Geometric skinning methods are highly efficient but struggle with artifacts such as collapsing joints or self‐intersections when animating inner anatomy along with the outer skin.
G. Nolte, F. Kemper, U. Schwanecke, M. Botsch   +3 more
wiley   +1 more source

A Triple-Hit Multi-Omics Framework for Psoriasis: Microbial Metabolic Remodeling and Immune Cell Methylome Signature Associated with an AMP-Dominant Lesional Program. [PDF]

Life (Basel)
Lee YK, Kim HY, Shim D.
europepmc   +1 more source