Results 41 to 50 of about 287,154 (333)

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer [PDF]

, 2014
FEN1 has key roles in Okazaki fragment maturation during replication, long patch base excision repair, rescue of stalled replication forks, maintenance of telomere stability and apoptosis.
Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abhik Mukherjee, Ajit Jadhav, Anton Simeonov, Bergh, Brown, Buterin, Carlos Caldas, Chin, Curtis, David J. Maloney, David M. Wilson, Devika Agarwal, Dorjbal Dorjsuren, Dorjsuren, Graham Ball, Guo, Henneke, Henneke, Hongmao Sun, Hothorn, Ian O. Ellis, Jennifer L. Illuzzi, Kim, Kim, Krause, Kucherlapati, Kucherlapati, Lam, Larsen, Larsen, Liu, McShane, Moggs, Nada Albarakati, Nikolova, Oscar M. Rueda, Paul Moseley, Pawitan, Rachel Abbotts, Roslin Russell, Sato, Schultz-Norton, Shen, Singh, Srinivasan Madhusudan, Stephen Chan, Sultana, Tarek M.A. Abdel-Fatah, van Pel, Vivek Mohan, Wu, Xu, Yang, Zheng, Zheng   +59 more
core   +2 more sources

Qualitative exploration of patients’ experiences with Intrabeam TARGeted Intraoperative radioTherapy (TARGIT-IORT) and External-Beam RadioTherapy Treatment (EBRT) for breast cancer

BMJ Open
Objective To gather a deep qualitative understanding of the perceived benefits and impacts of External-Beam RadioTherapy (EBRT) and TARGeted Intraoperative radioTherapy (TARGIT-IORT) using Intrabeam to assess how the treatments affected patient/care ...
Jayant S Vaidya, Siobhan Laws, Jennifer Royle, Sandeep Kumar Bagga, Natalie Swiderska, Charlotte Hooker, Marie Ennis-O'Connor, Siobhan Freeney, Dympna Watson, Robin Woolcock, George Lodge   +10 more
doaj   +1 more source

Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer [PDF]

, 2017
Triple negative breast cancer accounts for 15-20% of all breast cancer cases, but despite its lower incidence, contributes to a disproportionately higher rate of mortality.
Atale, Rutuja V., Hancock, Bradley A., Jones, David R., Pollok, Karen E., Radovich, Milan, Sinn, Anthony L., Solzak, Jeffrey P.   +6 more
core   +1 more source

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages [PDF]

, 2018
Background: As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control the angiogenic
Blandino, Giovanni, Donzelli, Sara, Fazi, Francesco, Fontemaggi, Giulia, Gallo, Enzo, Iosue, Ilaria, Masciarelli, Silvia, Melucci, Elisa, Milano, Elisa, Mottolese, Marcella, Pruszko, Magdalena, Sacconi, Andrea, Terrenato, Irene, Zylicz, Alicja, Zylicz, Maciej   +14 more
core   +3 more sources

Targeting KK-LC-1 inhibits malignant biological behaviors of triple-negative breast cancer

Journal of Translational Medicine, 2023
Background Cancer/testis antigens (CTAs) participate in the regulation of malignant biological behaviors in breast cancer. However, the function and mechanism of KK-LC-1, a member of the CTA family, in breast cancer are still unclear.
Xudong Zhu, Jiawen Bu, Tong zhu, Yi Jiang   +3 more
doaj   +1 more source

Prevalence of BRCA1 and BRCA2 gene mutations in Chinese patients with high‐risk breast cancer

Molecular Genetics & Genomic Medicine, 2019
Background Breast cancer is the most common cancer among women worldwide. Here, we report the prevalence of BRCA1/2 mutations in patients with high‐risk breast cancer from Inner Mongolia and Jilin, China, which was a part of a nationwide project on the ...
Xiaozhen Wang, Haimeng Liu, Amina Maimaitiaili, Gang Zhao, Sijie Li, Zheng Lv, Di Wu, Aiping Shi, Xin Guan, Hongyao Jia, Menghan Li, Dong Song, Lihua Kang, Bing Han, Tong Fu, Ming Yang, Zhu Zhu, Ye Du, Yanqiu Song, Jinghui Hong, Zhimin Fan   +20 more
doaj   +1 more source

Acinic cell carcinoma of the breast: A comprehensive review

Breast, 2022
Acinic cell carcinoma of the breast is a rare special subtype of breast cancer in the category of salivary gland-type tumors. It is morphologically similar to acinic cell carcinomas of salivary glands and pancreas and has a triple-negative phenotype ...
Azra Ajkunic, Faruk Skenderi, Nada Shaker, Saghir Akhtar, Janez Lamovec, Zoran Gatalica, Semir Vranic   +6 more
doaj   +1 more source

Breast cancer receptor status assessment and clinicopathological association in Nigerian women: A retrospective analysis [PDF]

, 2014
Background: Breast cancer markers are becoming increasingly important in breast cancer research due to their impact on prognosis, treatment and survival.
Ayodele, Sanni D., Javid, Farideh A., Makanjuola, Samira B.L., Obafunwa, John O., Oludara, Mobolaji A, Popoola, Abiodun O.   +5 more
core   +1 more source

Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan.

PLoS ONE, 2011
Discrepancies in the prognosis of triple negative breast cancer exist between Caucasian and Asian populations. Yet, the gene signature of triple negative breast cancer specifically for Asians has not become available. Therefore, the purpose of this study
Lee H Chen, Wen-Hung Kuo, Mong-Hsun Tsai, Pei-Chun Chen, Chuhsing K Hsiao, Eric Y Chuang, Li-Yun Chang, Fon-Jou Hsieh, Liang-Chuan Lai, King-Jen Chang   +9 more
doaj   +1 more source

PPARα-Selective Antagonist GW6471 Inhibits Cell Growth in Breast Cancer Stem Cells Inducing Energy Imbalance and Metabolic Stress

Biomedicines, 2021
Breast cancer is the most frequent cancer and the second leading cause of death among women. Triple-negative breast cancer is the most aggressive subtype of breast cancer and is characterized by the absence of hormone receptors and human epithelial ...
Vanessa Castelli, Mariano Catanesi, Margherita Alfonsetti, Chiara Laezza, Francesca Lombardi, Benedetta Cinque, Maria Grazia Cifone, Rodolfo Ippoliti, Elisabetta Benedetti, Annamaria Cimini, Michele d’Angelo   +10 more
doaj   +1 more source