Results 51 to 60 of about 22,597 (261)

HPM-Match: A Generic Deep Learning Framework for Historical Landslide Identification Based on Hybrid Perturbation Mean Match

Remote Sensing
The scarcity of high-quality labeled data poses a challenge to the application of deep learning (DL) in landslide identification from remote sensing (RS) images.
Shuhao Ran, Gang Ma, Fudong Chi, Wei Zhou, Yonghong Weng   +4 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Perturbation-tuned triple spiral metamagnetism and tricritical point in kagome metal ErMn6Sn6

Communications Materials
Kagome materials are of topical interest for their diverse quantum properties linked with correlated magnetism and topology. Here, we report anomalous hydrostatic pressure (p) effect on ErMn6Sn6 through isobaric and isothermal-isobaric magnetization ...
Satya Shanmukharao Samatham, Jacob Casey, Adrienn Maria Szucs, Venkateswara Yenugonda, Christopher Burgio, Theo Siegrist, Arjun K. Pathak   +6 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Higgs production from anomalous gluon dynamics

Journal of High Energy Physics
We present a two-loop analysis of the contributions to Higgs production via gluon-gluon fusion arising from the triple-gluon operator in the Standard Model effective field theory (SMEFT).
Ulrich Haisch
doaj   +1 more source

A case of opsoclonus-myoclonus syndrome associated with breast cancer

Current Problems in Cancer: Case Reports
Opsoclonus-myoclonus syndrome (OMS) is a rare presenting complication of cancer that is thought to be related to autoimmune mediated perturbation of homeostasis of oculomotor and limb movement.
Sebastian Mohar, Naomi Fujioka, Todd Tuttle, Bruce Trautman, Emilian Racila, Jianling Yuan, Sean J. Pittock, David A. Potter   +7 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Dimerization of Acetic Acid in the Gas Phase—NMR Experiments and Quantum-Chemical Calculations

Molecules, 2020
Due to the nature of the carboxylic group, acetic acid can serve as both a donor and acceptor of a hydrogen bond. Gaseous acetic acid is known to form cyclic dimers with two strong hydrogen bonds.
Ondřej Socha, Martin Dračínský
doaj   +1 more source