Results 51 to 60 of about 112,151 (292)

N-fold Supersymmetry in Quantum Mechanics - Analyses of Particular Models - [PDF]

, 2001
We investigate particular models which can be N-fold supersymmetric at specific values of a parameter in the Hamiltonians. The models to be investigated are a periodic potential and a parity-symmetric sextic triple-well potential.
Andrianov A. A., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Aoyama H., Bagrov V. G., Balitsky I. I., Bogomolny E. B., Casahorrán J., Fernández C. D. J., Fernández C. D. J., Khare A., Klishevich S., Klishevich S. M., Klishevich S. M., Lee S.-Y., Masatoshi Sato, Rosas-Ortiz J. O., Samsonov B. F., Silvertrov P. G., Toshiaki Tanaka   +27 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Proposal for a cavity-induced measurement of the exchange coupling in quantum dots

Physical Review Research, 2022
In spin qubit arrays the exchange coupling can be harnessed to implement two-qubit gates and to realize intermediate-range qubit connectivity along a spin bus.
Florian Ginzel, Guido Burkard
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Solution for Time-Fractional Coupled Burgers Equations by Generalized-Laplace Transform Methods

Fractal and Fractional
In this work, nonlinear time-fractional coupled Burgers equations are solved utilizing a computational method, which is called the double and triple generalized-Laplace transform and decomposition method.
Hassan Eltayeb, Said Mesloub
doaj   +1 more source

Stochastically accelerated perturbative triples correction in coupled cluster calculations

The Journal of Chemical Physics
We introduce a novel algorithm that leverages stochastic sampling techniques to compute the perturbative triples correction in the coupled-cluster framework. By combining elements of randomness and determinism, our algorithm achieves a favorable balance between accuracy and computational cost.
Damour, Yann, Gallo, Alejandro, Scemama, Anthony   +2 more
openaire   +4 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes

Frontiers in Oncology, 2023
IntroductionDrug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes.MethodsIn this study, we applied a ...
Katharine Yu, Amrita Basu, Christina Yau, Denise M. Wolf, Hani Goodarzi, Sourav Bandyopadhyay, James E. Korkola, Gillian L. Hirst, Smita Asare, Smita Asare, Angela DeMichele, Nola Hylton, Douglas Yee, Laura Esserman, Laura van ‘t Veer, Marina Sirota, Marina Sirota   +16 more
doaj   +1 more source

Properties of Microlensing Central Perturbations by Planets in Binary Stellar Systems under the Strong Finite-Source Effect

, 2010
We investigate high-magnification events caused by planets in wide binary stellar systems under the strong finite-source effect, where the planet orbits one of the companions.
Albrow, Bennett, Byeong-Gon Park, Chung, Dong, Dong, Griest, Han, Han, Han, Janczak, Lee, Sun-Ju Chung, Udalski   +13 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source