Results 51 to 60 of about 151,657 (257)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Radiology Case Reports, 2023 The first case of synovial sarcoma was published in 1893. The disease is a type of primary malignancy of the soft tissues. It is a rare and aggressive neoplasm of unknown tissue origin, characterized by strong metastatic potential and poor prognosis. The
Aleksandar A. Georgiev, PhD +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2023 Transient transfection of mammalian cells using plasmid DNA is a standard method to produce adeno-associated virus (AAV) vectors allowing for flexible and scalable manufacture.
Laura P. van Lieshout +25 more
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A Note on Multiplicative Triple Fibonacci Sequences [PDF]
The Bulletin of Society for Mathematical Services and Standards, 2015 In this paper, multiplicative triple Fibonacci sequences have been discussed. Here the results obtained by Singh et.al [3] have been extended. Some new theorems have been established.
Satish Kumar, Hari Kishan, Deepak Gupta
openaire +1 more source
Block-avoiding point sequencings of directed triple systems [PDF]
Discrete Mathematics, 2020 A directed triple system of order $v$ (or, DTS$(v)$) is decomposition of the complete directed graph $\vec{K_v}$ into transitive triples. A $v$-good sequencing of a DTS$(v)$ is a permutation of the points of the design, say $[x_1 \; \cdots \; x_v]$, such that, for every triple $(x,y,z)$ in the design, it is not the case that $x = x_i$, $y = x_j$ and $z
Donald L. Kreher +2 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Triple HIV-1 Infection Is Associated With Faster CD4+ T-Cell Decline
Frontiers in Microbiology, 2020 HIV-1 dual infection occurs when an individual is simultaneously or sequentially infected with two or more genetically distinct HIV-1 strains. According to the number of infected strains, HIV-1 dual infection can be divided in double infection and triple
Yu Zhang +10 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source