Results 131 to 140 of about 9,480,720 (296)

Evaluation of bubbler sensors for In Situ measurement of density, liquid depth, and surface tension in molten salts

open access: yesChemical Engineering Journal Advances
Molten salts are employed as heat-transfer fluids in energy systems, including concentrated solar power, thermal-energy storage, and molten salt reactors.
Maria del Rocio Rodriguez-Laguna   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Steiner Triple System

open access: yes, 2023
In combinatorial mathematics Steiner triple system, denoted by ST S(v), is a type of block designs. It is a pair (S, T) where S is a set of v elements and T is a set made up of triples of S (also known as blocks), where each pair of S elements appears in
Wang, Qiannan
core  

The Evolution of Binaries Embedded Within Common Envelopes

open access: yesThe Astrophysical Journal
Triple stellar systems allow us to study stellar processes that cannot be attained in binary stars. The evolutionary phases in which the stellar members undergo mass exchanges can alter the hierarchical layout of these systems.
Alejandra Rosselli-Calderon   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Triple P - Positive Parenting Program: Discussion Groups [PDF]

open access: yes, 2015
FlyerA discussion group is a short, small group session run by a trained Triple P provider. Each session brings together about 10 or 12 parents who are facing the same parenting issue.
Barnardos, Triple P
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Which government policies to create sustainable food systems have the potential to simultaneously address undernutrition, obesity and environmental sustainability?

open access: yesGlobalization and Health
Introduction A transformation of food systems is urgently needed, given their contribution to three ongoing and interlinked global health pandemics: (1) undernutrition and food insecurity, (2) obesity and non-communicable diseases (NCDs), and (3) climate
Celia Burgaz   +9 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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